# Fulminant Myocarditis Following Gastric Bypass Surgery: A Case Report

**Authors:** Lela Kopaleishvili, Ivditi Okuashvili, Naia Amiranashvili, Nani Gonjilashvili, Mariam Lomidze, Tamaz Kheladze

PMC · DOI: 10.7759/cureus.102256 · Cureus · 2026-01-25

## TL;DR

A young woman developed severe heart inflammation 18 months after gastric bypass surgery, likely due to nutritional deficiencies, and recovered with intensive treatment.

## Contribution

Highlights the rare but severe complication of fulminant myocarditis linked to post-bariatric malnutrition and emphasizes the need for long-term monitoring.

## Key findings

- A 23-year-old woman developed fulminant myocarditis 18 months after gastric bypass surgery.
- Severe nutritional deficiencies were identified as a potential trigger for myocardial inflammation and cardiac collapse.
- Aggressive treatment including immunomodulation and nutritional repletion led to significant cardiac recovery.

## Abstract

Fulminant myocarditis (FM) is a rare, life-threatening inflammatory disease of the myocardium characterized by sudden, severe cardiac dysfunction and hemodynamic instability. It often necessitates high-dose inotropic support and mechanical circulatory assistance, with a high risk of short-term mortality. We describe a 23-year-old woman who developed FM 18 months after undergoing Roux-en-Y gastric bypass. She presented with cardiogenic shock and ventricular arrhythmias precipitated by a period of clinical non-adherence and discontinued nutritional supplementation. Infectious and autoimmune workups were negative, but profound micronutrient and trace element deficiencies were identified. Emergency management included mechanical ventilation, inotropes, immunomodulatory therapy, and aggressive nutritional repletion. Cardiac magnetic resonance imaging confirmed myocarditis. Over two months, her left ventricular ejection fraction improved from approximately 25% to 56%, accompanied by full clinical recovery. This case illustrates the potential role of severe post-bariatric malnutrition in triggering myocardial inflammation and cardiovascular collapse. It underscores the importance of early recognition, multidisciplinary management, including immunomodulatory and nutritional therapy, and the necessity of vigilant long-term follow-up in patients after bariatric surgery to prevent such catastrophic outcomes.

## Linked entities

- **Diseases:** cardiogenic shock (MONDO:0800175)

## Full-text entities

- **Genes:** TNNT2 (troponin T2, cardiac type) [NCBI Gene 7139] {aka CMD1D, CMH2, CMPD2, LVNC6, RCM3, TnTC}, GPT (glutamic--pyruvic transaminase) [NCBI Gene 2875] {aka AAT1, ALT, ALT1, GPT1, SGPT}, CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}, SLC17A5 (solute carrier family 17 member 5) [NCBI Gene 26503] {aka AST, ISSD, NSD, SD, SIALIN, SIASD}, ALB (albumin) [NCBI Gene 213] {aka FDAHT, HSA, PRO0883, PRO0903, PRO1341}
- **Diseases:** Inflammatory (MESH:D007249), circulatory collapse (MESH:D012769), syncopal episode (MESH:D013575), cardiogenic shock (MESH:D012770), lactic acidosis (MESH:D000140), myocardial edema (MESH:D004487), class III obesity (MESH:D009765), autoimmune (MESH:D001327), arrhythmias (MESH:D001145), cardiomyopathy (MESH:D009202), FM (MESH:D009205), metabolic (MESH:D008659), mitral regurgitation (MESH:D008944), trace element deficiencies (MESH:C565217), micronutrient deficiencies (MESH:D007153), Malnutrition (MESH:D044342), obstructive disease (MESH:D001157), nutrient malabsorption (MESH:D008286), Viral infections (MESH:D014777), hypokinesia (MESH:D018476), cardiovascular collapse (MESH:D002318), weight loss (MESH:D015431), leukocytosis (MESH:D007964), cardiac failure (MESH:D006333), B1 deficiency (MESH:C566196), cardiac complications (MESH:D006331), Keshan disease (MESH:C536166), Coma (MESH:D003128), Infectious (MESH:D003141), sepsis (MESH:D018805)
- **Chemicals:** vitamin D (MESH:D014807), oxygen (MESH:D010100), lactate (MESH:D019344), B12 (MESH:C034730), methylprednisolone (MESH:D008775), iron (MESH:D007501), norepinephrine (MESH:D009638), 25-hydroxyvitamin D (MESH:C104450), dobutamine (MESH:D004280), cholecalciferol (MESH:D002762), thiamine (MESH:D013831), Selenium (MESH:D012643), ATP (MESH:D000255), gadolinium (MESH:D005682), prednisone (MESH:D011241), vitamin B12 (MESH:D014805), dopamine (MESH:D004298), Magnesium (MESH:D008274)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12931567/full.md

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12931567/full.md

## References

18 references — full list in the complete paper: https://tomesphere.com/paper/PMC12931567/full.md

---
Source: https://tomesphere.com/paper/PMC12931567