# Epidemiology of Dry Eye in Patients With Autoimmune Disease

**Authors:** Nan-Ni Chen, Yu-Tung Huang, Chi-Chin Sun

PMC · DOI: 10.1001/jamanetworkopen.2025.60275 · JAMA Network Open · 2026-02-23

## TL;DR

This study explores how common and severe dry eye disease is in people with autoimmune diseases in Taiwan.

## Contribution

The study clarifies disease-specific characteristics of dry eye in autoimmune diseases using a cohort in Taiwan.

## Key findings

- Dry eye disease prevalence varies among autoimmune diseases.
- Ocular surface damage is observed in patients with autoimmune conditions.

## Abstract

This cohort study investigates the prevalence, onset, and ocular surface damage of dry eye disease across major autoimmune diseases to clarify disease-specific characteristics among patients in Taiwan.

## Linked entities

- **Diseases:** autoimmune disease (MONDO:0007179)

## Full-text entities

- **Diseases:** SLE (MESH:D008180), Autoimmune (MESH:D001327), Sjogren syndrome (MESH:D012859), ocular surface damage (MESH:D010534), vasculitis (MESH:D014657), inflammation (MESH:D007249), corneal ulcer (MESH:D003320), Crohn disease (MESH:D003424), ulcer (MESH:D014456), DED (MESH:D015352), rheumatoid arthritis (MESH:D001172), Keratitis (MESH:D007634), Catastrophic Illness (MESH:D002388)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

6 references — full list in the complete paper: https://tomesphere.com/paper/PMC12931465/full.md

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Source: https://tomesphere.com/paper/PMC12931465