This paper is marked retracted in the scholarly record (OpenAlex). Interpret its findings with caution.
RETRACTION: Trichosanthes kirilowii Ethanol Extract and Cucurbitacin D Inhibit Cell Growth and Induce Apoptosis through Inhibition of STAT3 Activity in Breast Cancer Cells
Evidence-Based Complementary and Alternative Medicine

Abstract
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Taxonomy
TopicsAdvances in Cucurbitaceae Research · Seed and Plant Biochemistry · Herbal Medicine Research Studies
RETRACTION: S. R. Kim, H. S. Seo, H.‐S. Choi, et al. “Trichosanthes kirilowii Ethanol Extract and Cucurbitacin D Inhibit Cell Growth and Induce Apoptosis through Inhibition of STAT3 Activity in Breast Cancer Cells,” Evidence-Based Complementary and Alternative Medicine 2013, no. 1 (2013): 975350, https://doi.org/10.1155/2013/975350.
The above article, published online on 30 September 2013 in Wiley Online Library (https://wileyonlinelibrary.com), has been retracted by John Wiley & Sons Ltd. The retraction has been agreed after an investigation into concerns raised by Archasia belfragei and Illex illecebrosus via PubPeer [1]. Specifically, the LC‐MS chromatogram in Figure 6a shares unexpected similarities with the mass spectrum in Figure 6b.
Further investigation also revealed unexpected similarities between the western blot band depicting Actin in Figure 3b and the band depicting Tubulin in Figure 4a.
Several attempts by the journal to contact the authors have not resulted in a response. As such, the results cannot be considered reliable.
The reference list from the paper itself. Each links out to its DOI / PubMed record.
- 1Archasia belfragei and Illex illecebrosus, “Trichosanthes kirilowii Ethanol Extract and Cucurbitacin D Inhibit Cell Growth and Induce Apoptosis through Inhibition of STAT 3 Activity in Breast Cancer Cells,” Pub Peer (2025): https://pubpeer.com/publications/EF 5D 85CE 1E 391FA 54CBFDFEC 5DED 09.10.1155/2013/975350 PMC 380612324194785 · doi ↗ · pubmed ↗
