# Relationship Between the Frequency of Complications After Open-Heart Surgery and Mean Platelet Volume

## TL;DR

This study found that higher mean platelet volume after open-heart surgery is linked to more postoperative complications.

## Contribution

The study explores MPV as a potential predictor of postoperative complications rather than just an associated factor.

## Key findings

- MPV values at 24th and 48th postoperative hours were significantly higher in patients with complications.
- Blood urea nitrogen and creatinine levels were also significantly higher in the complication group.
- Elevated MPV levels may help identify patients at higher postoperative risk.

## Abstract

Objectives: Postoperative complications remain a major cause of morbidity and mortality after open-heart surgery, and early identification of patients at risk is essential for improving outcomes. This study aimed to evaluate the relationship between mean platelet volume (MPV) and postoperative complications following open-heart surgery.

Methods: This retrospective study included 234 patients who underwent open-heart surgery between September 2014 and November 2016 at Istanbul University Cardiology Institute. Patients were divided into two groups based on the presence or absence of postoperative complications. MPV was analyzed as a potential predictive marker of postoperative complications rather than merely an associated parameter. The primary outcome was the occurrence of any postoperative complication. Comparisons between groups were unadjusted for potential confounders such as renal function and comorbidities.

Results: MPV values at the 24th and 48th postoperative hours were significantly higher in patients with complications (p = 0.005, 0.003). Blood urea nitrogen (BUN) and creatinine levels were also significantly higher in the complication group (p = 0.001).

Conclusion: Elevated postoperative MPV levels were associated with a higher frequency of complications after open-heart surgery. These findings suggest that MPV may serve as a useful marker for identifying patients at increased postoperative risk.