# Clinical utility of evoked potentials for programming subthalamic deep brain stimulation in Parkinsons disease

## TL;DR

This paper reviews how evoked potentials can help improve deep brain stimulation programming for Parkinson's disease.

## Contribution

The paper evaluates evoked potentials as potential biomarkers for optimizing subthalamic deep brain stimulation programming.

## Key findings

- Evoked potentials may provide objective evidence for STN-DBS programming.
- Literature suggests potential clinical utility of evoked potentials in reducing side effects.
- Integration of electrophysiological data could streamline STN-DBS adjustments.

## Abstract

Optimal subthalamic nucleus deep-brain stimulation (STN-DBS) for Parkinson’s disease reduces motor symptoms without stimulating adjacent structures and causing side-effects. Fine-tuning STN-DBS using clinical evaluation is time-consuming and often requires multiple follow-ups. Electrophysiological recordings may enhance STN-DBS device programming for clinicians by providing objective evidence of neural pathway activation. This literature review critically evaluates evoked potentials as biomarkers of optimal STN-DBS and assesses potential integration into the device programming toolkit.