# Evolving relationships between air pollution attenuation and AECOPD hospitalizations during a stringent control period in Shijiazhuang, China, 2017–2024

**Authors:** Jingsi Cao, Zihan Ren, Xinyue Liu, Yanan Guo, Yunqian Wei, Xixin Yan

PMC · DOI: 10.3389/fpubh.2026.1741666 · Frontiers in Public Health · 2026-02-10

## TL;DR

This study shows that air pollution control in Shijiazhuang led to fewer hospitalizations for chronic obstructive pulmonary disease and weaker links between pollution and health.

## Contribution

The study reveals how stringent air pollution control reduces AECOPD hospitalizations and weakens pollutant-health associations over time.

## Key findings

- PM2.5, PM10, and SO2 concentrations decreased by 46%, 68%, and 85% during 2017–2024.
- PM2.5-attributable excess cases under WHO standards dropped by 37.1%.
- The relative risk between pollutants and AECOPD hospitalizations significantly attenuated over time.

## Abstract

Shijiazhuang, a typical industrial city, faced severe air pollution that elevated AECOPD risk. The period 2017–2024 coincided with stringent air pollution control, providing a key window to examine the evolving relationship between air quality improvements and AECOPD hospitalizations.

We analyzed 57,782 AECOPD hospitalizations (2017–2024) and air pollution data using a generalized additive Poisson time-series model. The analysis incorporated distributed lag non-linear terms while adjusting for meteorological conditions, seasonal trends, and day-of-week effects, with sensitivity analyses confirming result reliability.

PM2.5, PM10, and SO2 concentrations fell by 46%, 68%, and 85%, respectively. PM2.5-attributable excess cases under WHO standards dropped by 37.1%. Crucially, the association strength (relative risk) between most pollutants and hospitalizations showed a significant attenuating trend over time.

During this stringent air pollution control period in Shijiazhuang, marked air quality improvements were associated with reduced AECOPD hospitalizations and attenuated pollutant-health associations. Persistent ozone pollution highlights the need for coordinated VOC-NOx management.

## Linked entities

- **Chemicals:** SO2 (PubChem CID 1119)

## Full-text entities

- **Diseases:** toxicity (MESH:D064420), cough (MESH:D003371), immune dysfunction (MESH:D007154), COVID-19 (MESH:D000086382), death (MESH:D003643), asthma (MESH:D001249), lung cancer (MESH:D008175), dyspnea (MESH:D004417), influenza (MESH:D007251), inflammation (MESH:D007249), Acute Exacerbation of COPD (MESH:D029424)
- **Chemicals:** NOx (-), O3 (MESH:D010126), SO2 (MESH:D013458), PM (MESH:D011399), NOx (MESH:D009589), carbon (MESH:D002244), CO (MESH:D002248), NO2 (MESH:D009585), VOC (MESH:D055549)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12929520/full.md

## References

56 references — full list in the complete paper: https://tomesphere.com/paper/PMC12929520/full.md

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Source: https://tomesphere.com/paper/PMC12929520