# Patterns and predictors of repeated violent suicide attempts: a retrospective clinical study from an acute trauma care setting

**Authors:** Noemi Monika Szeifert, Lajos Balint, Xenia Gonda

PMC · DOI: 10.3389/fpsyt.2026.1736615 · Frontiers in Psychiatry · 2026-02-10

## TL;DR

This study identifies risk factors for repeated violent suicide attempts, highlighting the importance of early psychiatric care in trauma settings.

## Contribution

The study reveals new predictors of repeated violent suicide attempts, particularly among males with substance abuse and psychiatric disorders.

## Key findings

- Males had threefold higher odds of transitioning from non-violent to violent suicide methods.
- Polytoxicomania was associated with nearly fourfold higher odds of repetition.
- A prior violent suicide attempt was the strongest predictor of repetition (OR ≈ 660).

## Abstract

Violent suicide attempts pose a major challenge to trauma and psychiatric services due to their high lethality and complex clinical profiles. While non-violent suicidal behaviors have been extensively studied, considerably less is known about the recurrence of violent suicide attempts. This study examined demographic and clinical factors associated with repeated violent suicide attempts in Hungary.

A retrospective chart review was conducted at the Dr. Manninger Jenő National Trauma Center in Budapest among patients admitted between January 2015 and December 2024 following a violent suicide attempt. Electronic health records provided sociodemographic, psychiatric, motivational, and method-related data. Subgroup and logistic regression analyses were used to identify predictors of repetition.

The final sample comprised 327 individuals (222 males, 105 females; mean age = 46.95 years, SD = 19.5). Repeated violent suicide attempts were observed in 18% of females and 10% of males. Overall, 31% of violent suicide attempters had a history of a prior non-violent suicide attempt followed by a transition to violent methods. Males had approximately threefold higher odds of transitioning from non-violent to violent methods. Among suicide deaths, 76% occurred in males, and 96% were fatal at the first attempt. Personality disorders (OR = 4.15, p = 0.028), substance use disorders (OR = 2.86, p = 0.005), and sedative/hypnotic medication dependence (OR = 3.72, p = 0.009) were significantly associated with repeated violent suicide attempts, particularly among males. Polytoxicomania was associated with nearly fourfold higher odds of repetition (OR = 3.97, p = 0.0004). A history of a prior violent suicide attempt was the strongest predictor of repetition (OR ≈ 660, p < 0.000001), independent of age and sex. Acute psychotic symptoms, while not inherently motivational in themselves, emerged as the most frequently reported proxy associated with violent suicide among repeat attempters, followed by relational conflict, existential crisis, and chronic illness.

Repeated violent suicide attempts constitute a distinct and exceptionally high-risk clinical phenotype. Prior violent attempts, male sex in the context of repetition, personality disorders and substance abuse—particularly polytoxicomania—emerged as salient risk markers. These behaviors appear to arise at the intersection of prior violent conduct and acute substance-induced psychopathological states, notably psychotic symptoms with impaired reality testing and heightened impulsivity. Early identification and integrated psychiatric care, initiated during acute trauma management and maintained throughout rehabilitation, are critical to mitigating subsequent suicide risk in this vulnerable population.

## Full-text entities

- **Diseases:** MEDICATION (MESH:D000069279), alcohol intoxication (MESH:D000435), acute stress disorder (MESH:D040701), bipolar disorder (MESH:D001714), accidental injuries (MESH:D000081084), Personality disorders (MESH:D010554), NSSI (MESH:D012652), mood disorders (MESH:D019964), impulsivity (MESH:D007174), -IV (MESH:D006011), SCID (MESH:D020914), falls (MESH:C537863), chronic pain (MESH:D059350), depression (MESH:D003866), anxiety disorders (MESH:D001008), cognitive disorganization (MESH:D003072), chronic illness (MESH:D002908), emotional dysregulation (MESH:D021081), multiple sclerosis (MESH:D009103), borderline or antisocial personality traits (MESH:D000987), substance misuse (MESH:D009293), neuroendocrine (MESH:D018358), neurodevelopmental disorders (MESH:D002658), spinal cord damage (MESH:D013118), post-traumatic stress disorder (MESH:D013313), fractures (MESH:D050723), intellectual disabilities (MESH:D008607), psychotic phenomena (MESH:C566007), delusions (MESH:D063726), death (MESH:D003643), Alcohol abuse (MESH:D000437), psychotic spectrum disorders (MESH:D019967), amputation (MESH:C565682), Trauma (MESH:D014947), hallucinations (MESH:D006212), epilepsy (MESH:D004827), traumatic brain injury (MESH:D000070642), bodily injury (MESH:D009440), anxiety (MESH:D001007), violent conduct (MESH:D054537), Substance use disorders (MESH:D019966), Violent suicide (MESH:D001523), impaired judgment (MESH:D060825), permanent disability (MESH:D003638), COVID-19 (MESH:D000086382), poisoning (MESH:D011041), neuropsychiatric (MESH:C000631768), cancer (MESH:D009369), Psychotic symptoms (MESH:D011618)
- **Chemicals:** alcohol (MESH:D000438)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

79 references — full list in the complete paper: https://tomesphere.com/paper/PMC12929427/full.md

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Source: https://tomesphere.com/paper/PMC12929427