# Brain-inspired energy efficient technologies for next-generation artificial intelligence

**Authors:** Hillel J. Chiel, Jay S. Coggan, Gourav Datta, Jean-Marc Fellous, William R. P. Nourse, Roger D. Quinn, Peter J. Thomas

PMC · DOI: 10.1007/s00422-026-01038-4 · Biological Cybernetics · 2026-02-23

## TL;DR

This paper explores how brain-inspired principles can lead to more energy-efficient AI technologies to reduce the environmental impact of AI infrastructure.

## Contribution

The paper proposes neurobiological principles as a novel source of inspiration for developing energy-efficient NeuroAI.

## Key findings

- AI infrastructure is consuming vast resources with significant climate impacts.
- Neurobiological principles offer under-exploited inspiration for energy-efficient computing.
- Partnerships between industry and academia are needed to advance this research.

## Abstract

Since the advent of widely accessible AI tools, AI technology has been in high demand by businesses, academic researchers and individuals. Technology companies are building AI infrastructure at a rapid pace, and these facilities consume vast and growing resources, particularly electricity and water, with significant real and projected climate impacts. There is a need for new research initiatives to support long time horizon efforts to develop energy efficient computing capabilities to support the continued growth of AI infrastructure in a sustainable fashion. Such efficiency is required at both the hardware and software levels. Where can industry turn for examples of ultra-low power, energy efficient computing? We argue here that neurobiological principles offer rich and under-exploited sources of inspiration for energy efficient NeuroAI, and that new partnerships between industry and academia should be developed in this direction.

## Full-text entities

- **Diseases:** LLMs (MESH:D007806), depression (MESH:D003866), inflammation (MESH:D007249), hallucinations (MESH:D006212), pain (MESH:D010146)
- **Chemicals:** acetylcholine (MESH:D000109), norepinephrine (MESH:D009638), dopamine (MESH:D004298), Glucose (MESH:D005947), serotonin (MESH:D012701), calcium ion (-), silicon (MESH:D012825), potassium (MESH:D011188), sodium (MESH:D012964)
- **Species:** Mus musculus (house mouse, species) [taxon 10090], Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12929283/full.md

## References

6 references — full list in the complete paper: https://tomesphere.com/paper/PMC12929283/full.md

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Source: https://tomesphere.com/paper/PMC12929283