# Do we need a health technology assessment approach for non-inferiority specifically? A comment on: clinical equivalence and non-inferiority within health technology assessment by Taylor et al. (2025)

## TL;DR

The paper comments on the need for a balanced approach in health technology assessment when evaluating non-inferior treatments.

## Contribution

The paper emphasizes that non-inferior technologies should be assessed by weighing their advantages and deficits, similar to superior technologies.

## Key findings

- HTA of non-inferior technologies should balance potential advantages against deficits.
- Current non-inferiority analysis practices in HTA should be critically reviewed for fairness and accuracy.

## Abstract

Taylor and colleagues presented a very informative and comprehensive overview on the current practice of performing non-inferiority analysis in HTA. We would like to point out that HTA of potentially non-inferior technologies should be based on balancing potential advantages against potential deficits exactly as for potentially superior technologies.