# Complications after open fractures in children and adolescents - a single-center retrospective observational study

**Authors:** Alexis Brinkemper, Vanessa Marx, Thomas A. Schildhauer, Christiane Kruppa

PMC · DOI: 10.1007/s00068-026-03109-4 · European Journal of Trauma and Emergency Surgery · 2026-02-23

## TL;DR

This study examines complications and antibiotic treatment in children and adolescents with open fractures at a trauma center.

## Contribution

The study provides insights into factors associated with complications in pediatric open fractures.

## Key findings

- Complications are linked to injury severity, treatment methods, and injury localization.
- External fixation and non-primary wound closure correlate with complications.
- Antibiotic treatment was not found to correlate with complication occurrence.

## Abstract

Purpose of the study was to report the antibiotic treatment and complications after open fractures in children and adolescents at a level one trauma center.

We retrospectively report data of 72 children and adolescents with 74 open fractures. The open fractures were evaluated according to severity, etiology, localization, concomitant injuries, therapeutic treatment, concomitant antibiotic treatment, complications and outcome.

We found a significant relationship between the occurrence of complications and the severity of the open fractures, the treatment method, the mechanism of injury and for the localization. A correlation between the occurrence of complications and the antibiotic treatment could not be shown.

As the degree of injury increases, so does the likelihood of complications. There is also a correlation to treatment with external fixation, non-primary wound closure, traffic accidents and when the lower leg or foot is affected. However, the cause-and-effect relationship should always be considered.

## Full-text entities

- **Diseases:** Infection (MESH:D007239), pseudarthrosis (MESH:D011542), compartment syndrome (MESH:D003161), wound infection (MESH:D014946), extensor paresis (MESH:D010291), foot injury (MESH:D018409), tibial fracture (MESH:D013978), Complications (MESH:D008107), injuries (MESH:D014947), forearm and tibia fractures (MESH:D000092503), open injuries (MESH:D006259), III (MESH:C537189), Lisfranc fractures (MESH:D050723), pain (MESH:D010146), II (MESH:C537730), Open fractures (MESH:D005597), crushed (MESH:D003444), necrosis (MESH:D009336), peroneal lesion (MESH:D020427), septic (MESH:D001170), MRSA (MESH:D013203), fracture of the tibia (MESH:C535563), contracture (MESH:D003286), chronic pain (MESH:D059350), nerve lesion (MESH:D020426), malalignment (MESH:D017760), extremity (MESH:C563475), Osteomyelitis (MESH:D010019), traffic accident (MESH:D000081084)
- **Chemicals:** cephalosporin (MESH:D002511), Methicillin (MESH:D008712), Cefazolin (MESH:D002437)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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Source: https://tomesphere.com/paper/PMC12929258