# Retrospective cohort study evaluating patient-reported outcomes following intensive electromyography and video-biofeedback training in chronic non-flaccid facial palsy

**Authors:** Annika Kunzler, Susanne Hesse, Katharina Geißler, Jonas Ballmaier, Helene Kreysa, Christian Dobel, Susanne Saal, Orlando Guntinas-Lichius, Gerd Fabian Volk

PMC · DOI: 10.3389/fneur.2026.1759106 · Frontiers in Neurology · 2026-02-10

## TL;DR

A two-week EMG and video-biofeedback program significantly improved facial function and quality of life in patients with chronic facial palsy.

## Contribution

This study provides evidence for the effectiveness of an intensive EMG and video-biofeedback rehabilitation program in chronic non-flaccid facial palsy.

## Key findings

- Significant improvements in facial function and quality of life were observed after the two-week program.
- Improvements were sustained at six-month follow-up, with outcomes remaining above baseline.
- Age and gender were associated with differences in outcomes, emphasizing the need for individualized approaches.

## Abstract

Chronic non-flaccid peripheral facial palsy is frequently associated with synkinesis, residual motor deficits, and reduced quality of life. Evidence-based, standardized rehabilitation protocols remain limited. This study examined the effect of an intensive two-week electromyography (EMG) and video-based biofeedback program on changes in physical and psychosocial patient-reported outcomes in patients with chronic facial palsy.

This retrospective cohort study included patients with chronic non-flaccid facial palsy, either with synkinesis or residual hypotonia, who completed a two-week EMG and video-biofeedback program between 2020 and 2023. The intervention targeted synkinetic co-activation and improved voluntary motor control in hypotonia. Data consisted of routine documentation and patient-reported outcome measures (PROMs) collected at baseline 6 months before therapy (T1), therapy initiation (T2), therapy conclusion (T3), and six-month follow-up (T4). PROMs included the Facial Disability Index (FDI), Facial Clinimetric Evaluation Scale (FaCE), Short Form-36 Health Survey (SF-36), and Beck Depression Inventory (BDI). Analyses used repeated-measures ANOVA and segmented regression.

A total of 175 patients were included. Significant improvements were observed across all PROMs. From T2 to T3, FDI total score increased by 5.24 points (95% CI 3.90 to 6.60) and FaCE total score by 9.86 points (95% CI 7.80 to 11.92). SF-36 showed improvements in social functioning (+4.67 points, 95% CI 2.19 to 7.15) and emotional well-being (+4.32 points, 95% CI 2.60 to 6.00). BDI decreased by 3.29 points (95% CI –4.63 to −1.96). Segmented regression indicated small but significant pre-therapy improvements from T1 to T2. At follow-up, outcomes remained above baseline, with FDI total score rising from 65.64 ± 14.88 at T1 to 75.31 ± 13.83 at T4 and FaCE total score from 53.89 ± 16.54 to 63.72 ± 17.10 (all p < 0.001). Older age was associated with lower FDI values; male gender was associated with higher FDI and FaCE and lower BDI scores.

Participation in an intensive EMG- and video-based biofeedback program was associated with clinically relevant and sustained improvements in facial function, quality of life, and psychosocial well-being in patients with chronic non-flaccid facial palsy. Age- and gender-related differences highlight the importance of individualized rehabilitation approaches.

## Full-text entities

- **Diseases:** vestibular schwannomas (MESH:D009464), neuromuscular dysfunctions (MESH:D009468), mucoepidermoid carcinoma (MESH:D018277), synkinesis (MESH:D046608), motor deficits (MESH:D009461), post-COVID-19 (MESH:D000094024), motor disorders (MESH:D000068079), Facial palsy (MESH:D005158), incomplete eye closure (MESH:D015812), Ramsay Hunt Syndrome (MESH:D016697), Chronic peripheral facial palsy (MESH:C565028), Depression (MESH:D003866), Facial Comfort (MESH:D005153), mood disturbances (MESH:D019964), stroke (MESH:D020521), pain syndromes (MESH:C538101), paralysis (MESH:D010243), fatigue (MESH:D005221), facial weakness (MESH:D018908), benign neoplasms (MESH:D009369), CD (MESH:D003424), hypertonic facial palsy (MESH:D009122), flaccid paralysis (MESH:C000629404), PROM (MESH:D005322), adenoid cystic carcinoma (MESH:D003528), inflammatory (MESH:D007249), complete flaccidity (MESH:D009123), nerve injury (MESH:D000080902)
- **Species:** Human alphaherpesvirus 3 (Varicella-zoster virus, no rank) [taxon 10335], Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

42 references — full list in the complete paper: https://tomesphere.com/paper/PMC12929104/full.md

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Source: https://tomesphere.com/paper/PMC12929104