# Successful Management of Candida auris Bloodstream Infection in an Elderly Patient: A Case Report

## TL;DR

A 74-year-old man in Bangladesh with a drug-resistant Candida auris infection was successfully treated with micafungin after accurate diagnosis.

## Contribution

Demonstrates successful treatment of C. auris using rapid molecular identification and targeted antifungal therapy in a resource-limited setting.

## Key findings

- C. auris was identified using Vitek 2 and ITS sequencing, confirming its global phylogenetic clustering.
- The isolate showed resistance to fluconazole and amphotericin B but susceptibility to echinocandins.
- The patient fully recovered after 21 days of micafungin treatment.

## Abstract

Candida auris is an emerging multidrug‐resistant pathogen frequently misidentified by conventional methods, posing diagnostic and infection‐control challenges, particularly in low‐ and middle‐income countries. We report a 74‐year‐old male in Dhaka, Bangladesh, with multiple comorbidities who developed Candidemia. Blood culture yielded Gram‐positive budding yeast with inconclusive conventional carbohydrate tests. The isolate was identified as
C. auris
using Vitek 2 (software v8.01) and confirmed by ITS sequencing (GenBank accession MZ323988). Phylogenetic analysis showed clustering with global strains. Antifungal susceptibility testing indicated resistance to fluconazole and amphotericin B, with susceptibility to echinocandins. Intravenous micafungin was started based on susceptibility results and guideline recommendations. The patient responded gradually to the treatment, recovered fully, and was discharged after 21 days of admission. This case highlights the importance of rapid species‐level identification and access to confirmatory molecular testing to guide effective treatment and infection prevention in resource‐limited settings.

Candida auris is an emerging multidrug‐resistant pathogen often misidentified as other yeast types. Accurate identification of C. auris remains challenging in routine laboratories. This case demonstrates how rapid species‐level diagnosis combined with targeted antifungal therapy can ensure recovery, even in elderly patients with multiple comorbidities.