# Effect of digital chemotherapy extravasation education based on Orem’s self‐care theory in cancer patients: A quasi-experimental study

**Authors:** Hang Thi Nguyet Ho, Trang Thi Kieu Duong, Nguyet Thi Tran, Phuong Thi Anh Nguyen, Trang Thi Thuy Ho, Duc Nu Minh Ton

PMC · DOI: 10.1371/journal.pone.0343000 · PLOS One · 2026-02-23

## TL;DR

A digital education program based on Orem’s self-care theory improved cancer patients' knowledge and self-care abilities regarding chemotherapy extravasation.

## Contribution

This study demonstrates the effectiveness of integrating digital education with Orem’s self-care theory to enhance self-efficacy and self-care in cancer patients.

## Key findings

- The intervention group showed significant improvements in knowledge, self-care abilities, and self-efficacy compared to the control group.
- Digital technology was perceived as highly useful and easy to use, contributing to better outcomes over time.
- Qualitative results highlighted enhanced emotional resilience and readiness for self-care among participants.

## Abstract

Digital health education is crucial in preventing and managing chemotherapy extravasation among cancer patients. We aimed to evaluate the effectiveness of a digital chemotherapy extravasation educational intervention on knowledge, self-care abilities, and self-efficacy in cancer patients.

A quasi-experimental longitudinal design was conducted with 80 cancer patients at Hue University of Medicine and Pharmacy Hospital, Vietnam, from September 2022 to November 2023. The control group (n = 40) received routine health education on chemotherapy extravasation, while the experimental group (n = 40) participated in an extravasation education program based on Orem’s Self-Care Theory and utilized digital technology. This study assessed knowledge levels, self-care abilities, self-efficacy in preventing and managing chemotherapy extravasation, and the effectiveness of digital technology applications at three different time points. Chi-square tests, independent t-tests, and Analysis of Variance with Repeated Measures were employed to analyze the data.

There were statistically significant differences in knowledge (F = 16.24, p < 0.001), self-care abilities (F = 35.37, p < 0.001), and self-efficacy (F = 46.27, p < 0.001) between the intervention and control groups over time, with the intervention group showing greater improvements across all outcomes. Qualitative findings revealed three key categories: moving forward to self-care readiness, promoting emotional resilience, and enhancing a positive care environment. Patients perceived the digital technology applications as highly effective, especially in terms of perceived usefulness and ease of use, and showed significant changes across time (F = 9.93, p < 0.001).

Digital chemotherapy extravasation education based on Orem’s Self-Care Theory offers an effective approach that enhances cancer patients’ knowledge while strengthening their self-care. Therefore, healthcare providers should integrate digital education into routine patient care to enhance self-efficacy, reduce complications, and support better treatment outcomes.

## Linked entities

- **Diseases:** cancer (MONDO:0004992)

## Full-text entities

- **Diseases:** ovarian (MESH:D010049), necrosis (MESH:D009336), tissue injury (MESH:D017695), chronic illness (MESH:D002908), symptom (MESH:D012816), breast (MESH:D061325), colorectal (MESH:D015179), toxicity (MESH:D064420), ulceration (MESH:D014456), Extravasation (MESH:D005119), hearing impairment (MESH:D034381), blindness (MESH:D001766), critically ill (MESH:D016638), pain (MESH:D010146), skin irritation (MESH:D012871), Cancer (MESH:D009369), anxiety (MESH:D001007), swelling (MESH:D004487)
- **Chemicals:** Zalo (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

30 references — full list in the complete paper: https://tomesphere.com/paper/PMC12928399/full.md

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Source: https://tomesphere.com/paper/PMC12928399