# Invasive Pneumococcal Disease among Childbearing-Age Women, United States, 2007–2023

**Authors:** Namrata Prasad, Sopio Chochua, Bridget J. Anderson, Kathy M. Angeles, Meghan Barnes, Lee H. Harrison, Corinne Holtzman, Jessica R. Howard-Anderson, Shannon O’Brien, Susan Petit, Arthur Reingold, William Schaffner, Lesley McGee, Adam L. Cohen, Miwako Kobayashi

PMC · DOI: 10.3201/eid3202.251279 · Emerging Infectious Diseases · 2026-02-01

## TL;DR

This study examines how often invasive pneumococcal disease occurs in pregnant and postpartum women in the US compared to nonpregnant women.

## Contribution

The study provides new population-based incidence estimates for pneumococcal disease in pregnant and postpartum women.

## Key findings

- Pregnant women had similar pneumococcal disease rates as nonpregnant women of childbearing age.
- Postpartum women had 3.5 times higher disease incidence compared to nonpregnant women.
- Findings may help guide pneumococcal vaccination recommendations for these groups.

## Abstract

US data on invasive pneumococcal disease incidence among pregnant and postpartum women are limited. We estimated incidence in those groups using population-based surveillance. Compared with nonpregnant women of childbearing age, incidence was similar for pregnant women but 3.5 times higher for postpartum women. Our findings could inform pneumococcal vaccine recommendations.

## Full-text entities

- **Diseases:** leak (MESH:D019559), congenital or acquired asplenia (OMIM:271400), multiple myeloma (MESH:D009101), hemoglobinopathies (MESH:D006453), infection (MESH:D007239), malignancy (MESH:D009369), chronic heart, liver, or lung disease (MESH:D008171), abortion (MESH:D000026), chronic renal failure (MESH:D007676), diabetes mellitus (MESH:D003920), immunodeficiency (MESH:D007153), IPD (MESH:D011008), nephrotic syndrome (MESH:D009404), alcoholism (MESH:D000437), leukemia (MESH:D007938), HIV (MESH:D015658), Hodgkin disease (MESH:D006689), S. pneumoniae infection (MESH:D011014), sickle cell disease (MESH:D000755), bacterial infections (MESH:D001424), lymphoma (MESH:D008223), pregnancy loss (MESH:D000022)
- **Chemicals:** PCV (-)
- **Species:** Homo sapiens (human, species) [taxon 9606], Streptococcus pneumoniae (species) [taxon 1313]

## Full text

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## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12928246/full.md

## References

8 references — full list in the complete paper: https://tomesphere.com/paper/PMC12928246/full.md

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Source: https://tomesphere.com/paper/PMC12928246