# Using Routine Surveillance Data to Assess Dengue Virus Transmission Risk in Travelers Returning to the United States

## TL;DR

This paper uses US travel data to detect dengue virus transmission risks in foreign countries, offering a new way to monitor global dengue outbreaks.

## Contribution

A novel dual-criteria method using travel surveillance data to detect dengue transmission risks in countries with limited official reporting.

## Key findings

- Traveler-based surveillance accurately identified high-risk dengue periods in countries like Cuba.
- A >10-case threshold improved detection specificity for dengue risk.
- Timeliness of detection may decrease if reporting delays increase.

## Abstract

Dengue virus poses a growing global health threat, yet inconsistent local surveillance limits global risk assessments. We analyzed 10,530 travel-associated dengue cases among US travelers reported to ArboNET during January 2010–April 2024, involving travel to 128 countries. By using negative binomial and Poisson models, we developed country-specific thresholds (75th, 80th, 90th percentiles) to identify elevated travel-associated dengue risk. We applied a >10-case threshold in a 3-month period to improve specificity. The final dual-criteria method accurately identified high-risk periods, including sustained transmission in countries with limited official reporting, such as Cuba in 2022–2023. Threshold comparisons revealed a tradeoff between early detection and overclassification, whereas real-time and retrospective assessments revealed consistent high-risk signals. This traveler-based approach offers a timely, complementary method for travel-associated dengue risk detection, although timeliness might be reduced if reporting delays increase beyond our observations. Our findings support integrating travel surveillance into global dengue monitoring and preparedness efforts.