# Desulfovibrio Bacteremia in Patients with Abdominal Infections, Japan, 2020–2025

**Authors:** Naoki Watanabe, Tomohisa Watari, Yoshihito Otsuka

PMC · DOI: 10.3201/eid3202.251581 · Emerging Infectious Diseases · 2026-02-01

## TL;DR

This study examines eight cases of Desulfovibrio bacteremia in Japan from 2020 to 2025, identifying four species and detecting antibiotic resistance genes.

## Contribution

The study confirms the presence of specific Desulfovibrio species and identifies β-lactamase genes using genomic methods.

## Key findings

- Four Desulfovibrio species were confirmed using 16S rRNA gene and whole-genome sequencing.
- β-lactamase genes were detected in multiple Desulfovibrio species.
- Mass spectrometry failed to identify D. falkowii and D. legallii.

## Abstract

We reviewed 8 episodes of Desulfovibrio bacteremia in Japan (2020–2025) and confirmed 4 species by 16S rRNA gene and whole-genome sequencing. We detected β-lactamase genes in 2 D. desulfuricans (blaDES-1-like), 1 D. falkowii (blaMUN-1), and 2 D. fairfieldensis (blaCfiA-like). Mass spectometry failed to identify D. falkowii or D. legallii.

## Linked entities

- **Genes:** 16S rRNA (16S ribosomal RNA) [NCBI Gene 2597965]
- **Diseases:** bacteremia (MONDO:0005229)
- **Species:** Desulfovibrio desulfuricans (taxon 876), Desulfovibrio falkowii (taxon 3136602), Desulfovibrio fairfieldensis (taxon 44742), Desulfovibrio legallii (taxon 571438)

## Full-text entities

- **Diseases:** intraabdominal infections (MESH:D059413), abscesses (MESH:D000038), fever (MESH:D005334), cholecystitis (MESH:D002764), Desulfovibrio Bacteremia (MESH:D045824), Bacteremia (MESH:D016470), Abdominal Infections (MESH:D000007)
- **Chemicals:** metronidazole (MESH:D008795), sulfate (MESH:D013431), cefoxitin (MESH:D002440), oil (MESH:D009821), ceftriaxone (MESH:D002443), Piperacillin/tazobactam (MESH:D000077725), BACTEC (-), beta-lactams (MESH:D047090), ampicillin/sulbactam (MESH:C035444)
- **Species:** Desulfovibrio legallii (species) [taxon 571438], Parabacteroides goldsteinii (species) [taxon 328812], Desulfovibrio piger (species) [taxon 901], Brucella (genus) [taxon 234], Homo sapiens (human, species) [taxon 9606], Desulfovibrio fairfieldensis (species) [taxon 44742], Bacteroides fragilis (species) [taxon 817], Nitratidesulfovibrio vulgaris (species) [taxon 881]
- **Mutations:** C-37 C

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12928213/full.md

## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC12928213/full.md

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Source: https://tomesphere.com/paper/PMC12928213