# Rectal Arteriovenous Malformation Mimicking a Submucosal Tumor: Successful Long‐Term Outcome After Transcatheter Arterial Embolization With N‐Butyl‐2‐Cyanoacrylate‐Lipiodol

**Authors:** Hiroshi Baba, Masakazu Hirakawa, Takeshi Oda, Hiromu Hidaka, Masayuki Hirata, Sho Kakinouchi, Yasuko Tamaru, Yuji Abe, Yoshiki Asayama

PMC · DOI: 10.1002/deo2.70303 · DEN Open · 2026-02-21

## TL;DR

A rare rectal arteriovenous malformation was successfully treated with embolization, avoiding surgery and showing long-term improvement.

## Contribution

Demonstrates the effectiveness of transcatheter arterial embolization with N-butyl-2-cyanoacrylate-Lipiodol for rectal AVMs.

## Key findings

- Rectal AVMs can mimic submucosal tumors, requiring multimodal diagnosis.
- Embolization with NL led to lesion regression and no recurrence after 3 years.
- A post-treatment rectal ulcer was successfully managed with topical hydrocortisone.

## Abstract

Rectal arteriovenous malformations (AVMs) are rare vascular anomalies that pose diagnostic challenges because they may resemble submucosal tumor–like lesions. A 54‐year‐old man presented with recurrent hematochezia, and a colonoscopy revealed a protruding lesion near the dentate line. Contrast‐enhanced computed tomography and angiography confirmed a rectal AVM classified as Cho type IIIb/Yakes type II. Transcatheter arterial embolization with N‐butyl‐2‐cyanoacrylate–Lipiodol (NL) was performed. A rectal ulcer that developed 2 weeks after treatment was successfully managed with topical hydrocortisone. Follow‐up colonoscopy demonstrated progressive lesion regression without recurrence at 3 years. This case underscores that rectal AVMs may mimic submucosal tumors and require a multimodal diagnostic approach. Transcatheter arterial embolization with NL represents an effective therapeutic option.

## Linked entities

- **Chemicals:** hydrocortisone (PubChem CID 5754)

## Full-text entities

- **Diseases:** anemia (MESH:D000740), arterial obstruction (MESH:D001157), ulcer (MESH:D014456), NL (MESH:C536108), polyps (MESH:D011127), mucosal abnormalities (MESH:D052016), AVMs (MESH:D001165), enteritis (MESH:D004751), Cho type IIIb (MESH:D009084), TAE (MESH:D004617), vascular anomalies (MESH:D020785), chronic (MESH:D002908), gastrointestinal bleeding (MESH:D006471), ulcerative colitis (MESH:D003093), inflammation (MESH:D007249), Submucosal Tumor (MESH:D009369), edema (MESH:D004487), rectal AVM (MESH:D012002), bleeding (MESH:D006470), AVM (MESH:D002538), stenosis (MESH:D003251), mass (MESH:C536030)
- **Chemicals:** Lipiodol (MESH:D004998), NL (-), polyvinyl alcohol (MESH:D011142), barium (MESH:D001464), hydrocortisone (MESH:D006854), N-Butyl-2-Cyanoacrylate (MESH:D004659)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12928079/full.md

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12928079/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12928079/full.md

---
Source: https://tomesphere.com/paper/PMC12928079