# Successful Endoscopic Ultrasound‐Guided Transgastric Drainage for Intra‐Abdominal Abscess Caused by Delayed Perforation After Gastric Endoscopic Mucosal Resection

**Authors:** Fumiaki Tanino, Akinori Shimizu, Taiki Nobuto, Yasuhiro Okuda, Yudai Takehara, Masaki Wakai, Tetsuro Hirano, Seiji Onogawa, Keiji Hanada, Shinji Tanaka

PMC · DOI: 10.1002/deo2.70301 · DEN Open · 2026-02-21

## TL;DR

Endoscopic ultrasound-guided drainage successfully treated an intra-abdominal abscess caused by delayed perforation after gastric endoscopic mucosal resection.

## Contribution

Demonstrates the safety and effectiveness of EUS-guided transgastric drainage for treating IAA after gastric EMR.

## Key findings

- EUS-guided transgastric drainage resolved fever and inflammation in a patient with IAA.
- Follow-up imaging showed shrinkage of the abscess cavity after drainage.
- The procedure was effective when conservative therapy and percutaneous drainage were not feasible.

## Abstract

Delayed perforation after gastric endoscopic mucosal resection (EMR) is a rare but serious complication that can lead to intra‐abdominal abscess (IAA) formation. Efficacy of endoscopic ultrasound (EUS)‐guided drainage for IAA remains to be elucidated. A man in his 50s was admitted for EMR of hyperplastic polyps located in the gastric body. The procedure was performed uneventfully; however, on postoperative day (POD) 4, the patient developed a sudden fever accompanied by an elevation in inflammatory markers. Abdominal computed tomography (CT) revealed a localized area of increased fat attenuation, leading to a diagnosis of delayed perforation. The patient's condition temporarily improved with conservative therapy; however, fever and elevated inflammatory markers recurred on POD 17. CT demonstrated IAA requiring drainage. On POD 22, EUS‐guided transgastric drainage was performed using a nasobiliary drainage tube and double‐pigtail stent. After drainage, fever and inflammatory markers promptly alleviated; follow‐up CT demonstrated shrinkage of the abscess cavity. The clinical course was uneventful. EUS‐guided transgastric drainage could be a safe and effective therapeutic option for IAA secondary to delayed perforation after gastric EMR, particularly when conservative therapy fails and percutaneous drainage is not feasible.

## Full-text entities

- **Genes:** CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}
- **Diseases:** infection (MESH:D007239), peritonitis (MESH:D010538), ulcer (MESH:D014456), IAAs (OMIM:617082), anemia (MESH:D000740), IAA (MESH:D018784), hyperuricemia (MESH:D033461), necrotic (MESH:D009336), benign gastric lesions (MESH:D013272), abdominal tenderness (MESH:D000007), mucosal injury (MESH:D052016), bile reflux (MESH:D001655), gastric hyperplastic polyps (MESH:D011127), Perforation (MESH:D057112), tenderness (MESH:D063806), diabetes mellitus (MESH:D003920), ischemic necrosis (MESH:D005271), asthma (MESH:D001249), inflammatory (MESH:D007249), abscess (MESH:D000038), iron-deficiency anemia (MESH:D018798), fever (MESH:D005334), bleeding (MESH:D006470), obesity (MESH:D009765), gastric cancer (MESH:D013274)
- **Chemicals:** indigo carmine (MESH:D007203), amoxicillin (MESH:D000658), meropenem (MESH:D000077731)
- **Species:** Homo sapiens (human, species) [taxon 9606], Parvimonas micra (species) [taxon 33033]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12928046/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12928046/full.md

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Source: https://tomesphere.com/paper/PMC12928046