# Commentary on Gut Microbiome–Metabolome Alterations in Advanced Parkinson's Disease With Motor Complications

**Authors:** Hamza Rashid

PMC · DOI: 10.1002/cns.70789 · CNS Neuroscience & Therapeutics · 2026-02-23

## Full-text entities

- **Genes:** COMT (catechol-O-methyltransferase) [NCBI Gene 1312] {aka HEL-S-98n}
- **Diseases:** neurodegeneration (MESH:D019636), PD (MESH:D010300), dysbiosis (MESH:D064806), neuroinflammation (MESH:D000090862), neuronal dysfunction (MESH:D009461)
- **Chemicals:** levodopa (MESH:D007980), amino (-), dopaminergic (MESH:D004298), short-chain fatty acid (MESH:D005232)
- **Species:** Homo sapiens (human, species) [taxon 9606], gut metagenome (species) [taxon 749906]

## Full text

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## References

6 references — full list in the complete paper: https://tomesphere.com/paper/PMC12928009/full.md

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Source: https://tomesphere.com/paper/PMC12928009