# Evaluation of Postoperative Pain Frequency in Single‐Session Endodontic Treatments With Patency and Foraminal Enlargement

**Authors:** Viviane Barbosa Godoy, Ana Grasiela Limoeiro, Vanessa Sandini, Vini Mehta, Wayne Martins Nascimento, Marilia Fagury Videira Marceliano‐Alves, Marcos Frozoni

PMC · DOI: 10.1002/cre2.70313 · Clinical and Experimental Dental Research · 2026-02-23

## TL;DR

This study found that single-session endodontic treatments with foraminal instrumentation cause minimal postoperative pain, unaffected by factors like age, gender, or sealer type.

## Contribution

The study demonstrates that postoperative pain in single-session endodontic treatments is low and not influenced by several clinical variables.

## Key findings

- No significant differences in pain scores were found based on age, gender, tooth position, or sealer type.
- Most patients reported no or mild pain by 48 hours post-treatment.
- Pain levels decreased significantly after 48 hours for all variables analyzed.

## Abstract

This study aimed to evaluate the incidence of postoperative pain in single‐session endodontic treatments with foraminal instrumentation, considering factors such as pulpal diagnosis, tooth position, type of endodontic sealer, and sealer extrusion.

Treatments were performed on 153 teeth of patients aged 12–80 years diagnosed with asymptomatic irreversible pulpitis or asymptomatic pulpal necrosis with or without periapical lesions. The obturation sealers used were AH Plus, Endomethasone‐N, and Sealer Plus. Postoperative pain intensity was recorded by patients using a modified numerical rating scale (NRS) ranging from 0 (no pain) to 10 (severe pain).

No statistically significant differences in pain scores were found at 12, 24, or 48 h in relation to gender, age, tooth position, pulpal diagnosis, type of sealer, or extrusion (p > 0.05). The most common pain levels classified as uncomfortable were observed at 12 and 24 h, while 94.1% of patients reported no pain at 48 h; the remaining pain was mild. Pain scores decreased significantly after 48 h for all variables.

Single‐session endodontic treatment with foraminal instrumentation showed a low incidence of postoperative pain that was not influenced by the variables analyzed in this study.

The null hypothesis was that there was no association between the occurrence of postoperative pain and (i) age, (ii) patient gender, (iii) pulp diagnosis, (iv) tooth position, (v) endodontic sealer type, and (vi) sealer extrusion.

## Full-text entities

- **Diseases:** pulpitis (MESH:D011671), periapical lesion (MESH:D010483), pulpal necrosis (MESH:D003784), cytotoxicity (MESH:D064420), Postoperative Pain (MESH:D010149), calcifications (MESH:D002114), Pain (MESH:D010146), pulp necrosis (MESH:D003790), inflammation (MESH:D007249)
- **Chemicals:** eugenol (MESH:D005054), silicone (MESH:D012828), chlorhexidine (MESH:D002710), Zinc oxide (MESH:D015034), bisphenol A diglycidyl ether (MESH:C019273), Endomethasone (MESH:C011244), epinephrine (MESH:D004837), epoxy (MESH:D004853), Sealer Plus (MESH:C505571), calcium hydroxide (MESH:D002126), Dipyrone (MESH:D004177), EDTA (MESH:D004492), hydrocortisone (MESH:D006854), AH Plus (MESH:C534916), Septodont (MESH:C034472), Coltosol (-), lidocaine (MESH:D008012)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12927984/full.md

## References

42 references — full list in the complete paper: https://tomesphere.com/paper/PMC12927984/full.md

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Source: https://tomesphere.com/paper/PMC12927984