# Frequency of adverse feto-maternal outcomes in patient with placental abruption

**Authors:** Uzma Kausar, Saima Khattak

PMC · DOI: 10.12669/pjms.42.1.12261 · Pakistan Journal of Medical Sciences · 2026-01-01

## TL;DR

This study found high rates of serious complications in mothers and babies when placental abruption occurs during pregnancy.

## Contribution

The study provides updated frequency data on maternal and fetal complications specifically in placental abruption cases.

## Key findings

- 27.9% of mothers experienced postpartum hemorrhage and 19.1% had disseminated intravascular coagulation.
- 20.6% of fetuses had stillbirth and 22.1% were born prematurely.
- Maternal age was significantly linked to disseminated intravascular coagulation and stillbirth outcomes.

## Abstract

This study aimed to determine the frequency of adverse feto-maternal outcomes in patients with placental abruption.

This descriptive case series was a study carried out in the Department of Obstetrics and Gynecology, Lady Reading Hospital, Peshawar between January 26, 2022 and July 26, 2022. The sample size of the study was 136 patients who had placental abruption, who were aged between 18 and 40 years, and were more than 24 weeks of gestation and any parity. The feto-maternal outcomes of these patients were compared.

The mean age of the participants was 27.65 ± 6.27 years. The adverse maternal outcomes were acute tubular necrosis (8.8%), disseminated intravascular coagulation (19.1%), postpartum hemorrhage (27.9%), and maternal admission to ICU was detected in 7 (5.1%) patients. The maternal age was significant as associated with DIC (p < 0.05). Adverse fetal outcomes included intrauterine fetal death in 6 (4.4%), preterm birth in 30 (22.1%), low APGAR score in 33 (24.3%), stillbirth in 28 (20.6%), and admission to NICU in 29 (21.3%). The maternal demographic variables were significantly related to preterm birth (p = 0.03) and stillbirth (p < 0.05).

Our study identified the frequency of adverse fetal and maternal outcomes in patients with placental abruption. The fetal outcomes were intrauterine fetal death, pre-term births, low APGAR score, and stillbirth. The acute tubular necrosis, disseminated intravascular coagulation and postpartum hemorrhage were maternal outcomes.

## Linked entities

- **Diseases:** placental abruption (MONDO:0004846), acute tubular necrosis (MONDO:0006637), disseminated intravascular coagulation (MONDO:0001243)

## Full-text entities

- **Genes:** FGB (fibrinogen beta chain) [NCBI Gene 2244] {aka HEL-S-78p}
- **Diseases:** preeclampsia (MESH:D011225), urinary tract infection (MESH:D014552), blood loss (MESH:D016063), preterm birth (MESH:D047928), coagulation (MESH:D001778), Acute tubular necrosis (MESH:D007683), ischemic encephalopathy (MESH:D002545), placenta abruption (MESH:D010922), HELLP syndrome (MESH:D017359), diabetes (MESH:D003920), uterine rupture (MESH:D014597), hypertension (MESH:D006973), feto-maternal complication (MESH:D011248), anemia (MESH:D000740), cerebral palsy (MESH:D002547), disseminated intravascular coagulation (MESH:D004211), PA (MESH:D000037), respiratory distress (MESH:D012128), postpartum bleeding (MESH:D006473), acute renal failure (MESH:D058186), intrauterine fetal death (MESH:D005313), infant death (MESH:D066088), intracranial hemorrhage (MESH:D020300), Stillbirth (MESH:D050497), uterine anomalies (MESH:C562565), bleeding (MESH:D006470), hypoxic (MESH:D002534)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12927122/full.md

## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC12927122/full.md

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Source: https://tomesphere.com/paper/PMC12927122