# Acceleration of Atmospheric Freeze‐Drying of Food: Methods, Implications, Commercialization, and Future Directions

**Authors:** Nikita S. Bhatkar, Anarghya Ananda Murthy, Siew Young Quek, Meng Wai Woo

PMC · DOI: 10.1111/1541-4337.70432 · Comprehensive Reviews in Food Science and Food Safety · 2026-02-23

## TL;DR

Atmospheric freeze-drying is a cheaper alternative to traditional methods, but it takes longer, so researchers are exploring ways to speed it up for better commercial use.

## Contribution

This review evaluates methods to accelerate atmospheric freeze-drying and highlights the gap between research and commercial application.

## Key findings

- Thermal methods and vapor flow enhancement can speed up atmospheric freeze-drying.
- Internal resistance reduction and pretreatments also show potential for acceleration.
- There is a significant gap between research progress and commercial adoption of these methods.

## Abstract

Atmospheric freeze‐drying (AFD) is an emerging and cost‐effective alternative for drying food and pharmaceutical ingredients, offering lower investment and operational costs compared with vacuum freeze‐drying (VFD). However, industrial adoption is limited due to the significantly longer time required, resulting from consistently lower drying rates. This has led to increasing interest in accelerating AFD through various strategies. Several approaches have been explored, which can be classified as thermal methods, enhanced vapor flow, reduction in internal resistance, and other pretreatments. While these methods show some degree of acceleration, understanding their implications and limitations is essential for their adoption in AFD. Despite ongoing research on acceleration methods, the analysis of the commercial presence of AFD suggests a significant gap between research progress and the applicability of these methods. This review offers insight into these acceleration methods and provides some future considerations for research to enhance the viability of the process.

## Full-text entities

- **Diseases:** depression (MESH:D003866), AFD (MESH:D015352)
- **Chemicals:** ascorbic acid (MESH:D001205), alumina (MESH:D000537), free fatty acids (MESH:D005230), water (MESH:D014867), phospholipids (MESH:D010743), ertapenem (MESH:D000077727), activated carbon (MESH:D002244), nitrogen (MESH:D009584), Oxygen (MESH:D010100), salt (MESH:D012492), sugar (MESH:D000073893), ice (MESH:D007053), trehalose (MESH:D014199), hydrogen (MESH:D006859), tetrahydrofuran (MESH:C018674), mannitol (MESH:D008353), itraconazole (MESH:D017964), danazol (MESH:D003613), polyphenols (MESH:D059808), corn starch (MESH:D013213), zeolite (MESH:D017641), silica (MESH:D012822), AFD (-)
- **Species:** Allium sativum (garlic, species) [taxon 4682], Malus domestica (apple, species) [taxon 3750], Agaricus bisporus (common mushroom, species) [taxon 5341], Lathyrus oleraceus (garden pea, species) [taxon 3888], Brassica rapa subsp. rapa (turnip, subspecies) [taxon 51350], Bacteriophage sp. (species) [taxon 38018], Calanus finmarchicus (species) [taxon 6837], Solanum tuberosum (potatoes, species) [taxon 4113], Homo sapiens (human, species) [taxon 9606], Daucus carota (carrot, species) [taxon 4039], Solanum melongena (aubergine, species) [taxon 4111], Hexapoda (hexapods, subphylum) [taxon 6960]
- **Mutations:** C at 2, C for 20-26, C) at 2450, C for 24-28, C) at 2, C to -5, C for 12-20, C for 20-24, A 10 C, C at 3, C for 8-12, C for 28-34, C for 0-6, C for 6-20, C at 300

## Full text

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## Figures

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## References

77 references — full list in the complete paper: https://tomesphere.com/paper/PMC12926932/full.md

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Source: https://tomesphere.com/paper/PMC12926932