# A Prospective Observational Study on Maternal and Foetal Outcomes Among Primigravid Women With High Body Mass Index in a Tertiary Care Hospital in West Bengal

**Authors:** Kamal K Dash, Jayeeta Burman, Biplab Bala, Sembagamuthu Sembiah

PMC · DOI: 10.7759/cureus.102141 · Cureus · 2026-01-23

## TL;DR

This study examines how high BMI in first-time pregnant women affects maternal and fetal outcomes in a hospital in West Bengal.

## Contribution

The study provides new evidence on maternal and fetal risks associated with high BMI in primigravid women in an Indian context.

## Key findings

- High BMI was significantly associated with hypertensive disorders and gestational diabetes.
- Infants of high-BMI mothers had higher odds of preterm birth and NICU admission.

## Abstract

Context

Overweight and obesity among Indian women of reproductive age are increasing, posing important risks for pregnancy, particularly in primigravid women. Evidence focused solely on primigravid women remains limited.

Aim

This study aims to assess maternal and foetal outcomes among primigravid women with high body mass index (BMI) attending a tertiary care hospital in Kolkata.

Settings and design

This is a prospective observational study conducted over one year in a tertiary care obstetric unit.

Methods and materials

A total of 144 primigravid women enrolled at ≤12 weeks of gestation were categorised into normal BMI (18.5-24.9 kg/m²) and high BMI (≥25 kg/m²). Maternal outcomes included hypertensive disorders of pregnancy (HDP), gestational diabetes mellitus (GDM), labour and delivery complications. Foetal outcomes assessed were preterm birth, neonatal morbidity, and NICU admission. Logistic regression was used to estimate adjusted odds ratios (AOR).

Results

A high BMI was present in 40.3% of participants. High BMI was significantly associated with HDP and GDM. Labour complications and delivery complications were also more frequent. Infants of high-BMI mothers showed higher odds of being born preterm and of NICU admission.

Conclusions

High early-pregnancy BMI is an important predictor of adverse maternal and neonatal outcomes in primigravid women. Early BMI screening, focused antenatal surveillance, and preconception counselling are essential for risk reduction.

## Linked entities

- **Diseases:** gestational diabetes mellitus (MONDO:0005406)

## Full-text entities

- **Genes:** LEP (leptin) [NCBI Gene 3952] {aka LEPD, OB, OBS}, ADIPOQ (adiponectin, C1Q and collagen domain containing) [NCBI Gene 9370] {aka ACDC, ACRP30, ADIPQTL1, ADPN, APM-1, APM1}
- **Diseases:** thyroid disorders (MESH:D013959), Excess adiposity (MESH:D018205), Obesity (MESH:D009765), haemorrhage (MESH:D006470), neonatal hypoglycaemia (MESH:D007232), organ dysfunction (MESH:D009102), GDM (MESH:D016640), Anaemia (MESH:D000743), Overweight (MESH:D050177), PPH (MESH:D006473), metabolic (MESH:D008659), maternal (MESH:D000079262), proteinuria (MESH:D011507), prolonged labour (MESH:D008133), respiratory distress (MESH:D012128), Soft tissue (MESH:D017695), labour and delivery complications (MESH:D008107), LBW (MESH:D001724), inflammation (MESH:D007249), hypertension (MESH:D006973), HDP (MESH:D046110), preterm birth (MESH:D047928), macrosomia (MESH:D005320), diabetes mellitus (MESH:D003920), endothelial dysfunction (MESH:D014652), preeclampsia (MESH:D011225), dystocia (MESH:D004420), wound infection (MESH:D014946), dysregulated glucose metabolism (MESH:D044882), blood loss (MESH:D016063), Insulin resistance (MESH:D007333), bronchial asthma (MESH:D001249)
- **Chemicals:** glucose (MESH:D005947), blood glucose (MESH:D001786), oxygen (MESH:D010100)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

23 references — full list in the complete paper: https://tomesphere.com/paper/PMC12926700/full.md

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Source: https://tomesphere.com/paper/PMC12926700