# Concomitant occlusion of the deep dorsal vein and dorsal artery of the penis in a sickle cell anaemia patient

**Authors:** Thomas Saliba, Arnaud Bourguignon, Guillaume Fahrni

PMC · DOI: 10.1016/j.eucr.2026.103378 · Urology Case Reports · 2026-02-16

## TL;DR

This paper reports the first case of combined penile vein and artery blockage in a sickle cell patient, emphasizing the importance of Doppler ultrasound for diagnosis.

## Contribution

First reported case of combined deep dorsal penile vein and artery thrombosis in a sickle cell anaemia patient.

## Key findings

- Penile Mondor disease is rare and often underrecognized.
- Sickle cell anaemia increases the risk of both venous and arterial thrombosis in the penis.
- Doppler ultrasound is essential for diagnosing and assessing vascular conditions in such cases.

## Abstract

Penile Mondor disease is a rare, often underrecognized condition caused by thrombosis of the superficial dorsal penile vein; arterial thrombosis is even rarer. We report a 30-year-old man with sickle cell anaemia who presented with 10 days of painful erections and dorsal penile induration. Doppler ultrasound demonstrated deep dorsal penile vein and left dorsal penile artery thrombosis. Sickle cell anaemia confers a hypercoagulable state predisposing to venous and arterial thrombosis. This represents the first reported case of combined deep dorsal penile vein and artery thrombosis, highlighting the value of Doppler ultrasound and need for clinical suspicion in patients with coagulopathies.

•Penile Mondor disease is rare and frequently underrecognized.•First reported case of combined dorsal vein and artery thrombosis.•Sickle cell anaemia may predispose to penile venous and arterial thrombosis.•Doppler ultrasound is key for diagnosis and vascular assessment.

Penile Mondor disease is rare and frequently underrecognized.

First reported case of combined dorsal vein and artery thrombosis.

Sickle cell anaemia may predispose to penile venous and arterial thrombosis.

Doppler ultrasound is key for diagnosis and vascular assessment.

## Full-text entities

- **Diseases:** pulmonary embolism (MESH:D011655), hypercoagulability (MESH:D019851), priapism (MESH:D011317), dorsal penile indurations (MESH:D010411), arterial thrombosis (MESH:D002341), pain (MESH:D010146), pelvic tumour (MESH:D010386), Lapeyronie's disease (MESH:D004194), trauma (MESH:D014947), inflammation (MESH:D007249), necrosis (MESH:D009336), Sickle cell anaemia (MESH:D000755), haemolytic anaemia (MESH:D000743), organ damage (MESH:D000092124), Penile Mondor disease (MESH:D010409), sclerosing lymphangitis (MESH:D008205), venous and arterial thrombosis (MESH:D020246), SARS-COV-19 infection (MESH:D000086382), infection (MESH:D007239), coagulopathies (MESH:D001778), occlusion of the (MESH:D001157), blood (MESH:D006402), phlebitis (MESH:D010689), occlusion of the deep dorsal vein and (MESH:D012170), Thrombosis (MESH:D013927)
- **Chemicals:** apixaban (MESH:C522181), Cyproterone Acetate (MESH:D017373), warfarin (MESH:D014859)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12926608/full.md

## References

14 references — full list in the complete paper: https://tomesphere.com/paper/PMC12926608/full.md

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Source: https://tomesphere.com/paper/PMC12926608