# Subcellular targeting of survivin peptides: A multi-axis approach to cancer therapy

**Authors:** Anup Singh Pathania

PMC · DOI: 10.1016/j.omton.2026.201145 · Molecular Therapy Oncology · 2026-02-17

## Full-text entities

- **Genes:** CASP3 (caspase 3) [NCBI Gene 836] {aka CPP32, CPP32B, SCA-1}, CASP9 (caspase 9) [NCBI Gene 842] {aka APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56}, Birc5 (baculoviral IAP repeat-containing 5) [NCBI Gene 11799] {aka AAC-11, Api4, TIAP, survivin40}, Trp53-ps (transformation related protein 53, pseudogene) [NCBI Gene 22060], Antp (Antennapedia) [NCBI Gene 40835] {aka 3.4, ANT-C, ANT-P, ANTC, Ant, AntP1}, XIAP (X-linked inhibitor of apoptosis) [NCBI Gene 331] {aka API3, BIRC4, IAP-3, ILP1, MIHA, XLP2}, Diablo (diablo, IAP-binding mitochondrial protein) [NCBI Gene 66593] {aka 0610041G12Rik, 1700006L01Rik, Smac}, Det (Deterin) [NCBI Gene 42077] {aka CG12265, Dmel\CG12265, scpo, svn}, CD274 (CD274 molecule) [NCBI Gene 29126] {aka ADMIO5, B7-H, B7H1, PD-L1, PDCD1L1, PDCD1LG1}, CD47 (CD47 molecule) [NCBI Gene 961] {aka IAP, MER6, OA3}, HSP90AA1 (heat shock protein 90 alpha family class A member 1) [NCBI Gene 3320] {aka EL52, HEL-S-65p, HSP86, HSP89A, HSP90A, HSP90N}, Mki67 (antigen identified by monoclonal antibody Ki 67) [NCBI Gene 17345] {aka D630048A14Rik, Ki-67, Ki67}, CD8A (CD8 subunit alpha) [NCBI Gene 925] {aka CD8, CD8alpha, IMD116, Leu2, p32}, dbo (diablo) [NCBI Gene 53556] {aka CG6224, DIABLO, Dm.DBO, Dmel\CG6224, Smac, henji}
- **Diseases:** Tumor (MESH:D009369), lung cancer (MESH:D008175), breast, lung, melanoma, and prostate cancers (MESH:D001943), metastasis (MESH:D009362), cytotoxic (MESH:D064420)
- **Chemicals:** terameprocol (MESH:C076852), YM155 (MESH:C523798), FL118 (MESH:C578515), 1H13 (-), D (MESH:D003903), L-amino acids (MESH:D000596), shepherdin (MESH:C503112)
- **Species:** Mus musculus (house mouse, species) [taxon 10090], Drosophila melanogaster (fruit fly, species) [taxon 7227], Homo sapiens (human, species) [taxon 9606]
- **Cell lines:** A549 — Homo sapiens (Human), Lung adenocarcinoma, Cancer cell line (CVCL_0023), A549 lung cancer — Homo sapiens (Human), Lung squamous cell carcinoma, Cancer cell line (CVCL_3008)

## Full text

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## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12926545/full.md

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Source: https://tomesphere.com/paper/PMC12926545