# Determining optimal Barthel Index cutoff scores for predicting Longshi Scale grades across age groups in stroke patients

**Authors:** Jing Zhang, Mingchao Zhou, Ankang Liu, Ruixue Ye, Yulong Wang

PMC · DOI: 10.3389/fragi.2026.1701910 · Frontiers in Aging · 2026-02-09

## TL;DR

This study finds optimal Barthel Index cutoff scores for predicting disability levels in stroke patients across different age groups.

## Contribution

The study introduces age-stratified BI cutoff scores for LS grades, enabling consistent outcome interpretation in stroke care.

## Key findings

- BI cutoffs of ≥75, ≥45, and <5 correspond to LS grades ≥2, ≥4, and =6, respectively.
- Strong negative correlations (r = −0.879) were observed between BI scores and LS disability levels in older patients.
- AUC values >0.95 indicate excellent discriminative ability for the mildest and most severe disability levels.

## Abstract

The Barthel Index (BI) is a standard, widely used measure of dependence in activities of daily living (ADL), particularly in stroke care. The Longshi Scale (LS) offers a simpler, more user-friendly alternative; however, it lacks a validated, age-stratified mapping to BI scores. This gap limits consistent outcome interpretation and application.

This study aims to establish and validate a standardized, age-stratified concordance between BI scores and LS grades, thereby providing a practical conversion tool for clinical and research settings.

In a multi-center study of 16,412 stroke inpatients (3 months post-stroke), BI scores and LS grades were analyzed across age groups: <60 years (n = 12,662), 60–79 years (n = 2,596), and ≥80 years (n = 1,154). Sensitivity (correct identification) and specificity (correct exclusion), along with receiver operating characteristic (ROC) curves were used to determine optimal BI cutoff points for each LS grade. Spearman correlation and the Kruskal–Wallis test were applied across age groups.

Key BI cutoffs were identified for LS grades: ≥75 for LS ≥ 2, ≥45 for LS ≥ 4, and <5 for LS = 6. These cutoff values were consistent across age groups. The BI scores were negatively correlated with LS disability level (e.g., r = −0.879 in patients aged ≥80 years, p < 0.001). Correlations remained strongest at severe disability levels (LS grades 5–6) across age groups (r = −0.60 to −0.65). AUC analysis demonstrated excellent discriminative ability, particularly for the mildest (LS 1) and most severe (LS 6) disability levels (AUC >0.95).

The study provides age-stratified BI cutoff values to guide resource allocation, emphasizing the need to prioritize care for individuals aged ≥80 years with BI scores below 5.

## Linked entities

- **Diseases:** stroke (MONDO:0005098)

## Full-text entities

- **Diseases:** Stroke (MESH:D020521), disability (MESH:D009069), functional impairment (MESH:D003072), frailty (MESH:D000073496), LS (MESH:C538175), fractures (MESH:D050723), mobility-defined disabilities (MESH:D014086), ischemic or hemorrhagic stroke (MESH:D002543), long-term disability (MESH:D000088562), BI (MESH:C566784), Critical illness (MESH:D016638), declines (MESH:D060825), dependency (MESH:D019966)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

38 references — full list in the complete paper: https://tomesphere.com/paper/PMC12926473/full.md

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Source: https://tomesphere.com/paper/PMC12926473