# The effect of hypoxic interventions on swimming performance in competitive athletes: a systematic review and meta-analysis

**Authors:** Jiangzhou Chen, Taofeng Xing, Jianan Gong, Ditao Song

PMC · DOI: 10.3389/fphys.2026.1755641 · Frontiers in Physiology · 2026-02-09

## TL;DR

Hypoxic training slightly improves swimming performance in competitive athletes, particularly in short-distance events, but does not significantly affect key physiological metrics.

## Contribution

This study provides a systematic review and meta-analysis showing that hypoxic interventions modestly enhance swimming performance, likely through non-hematological adaptations.

## Key findings

- Hypoxic interventions led to a small but significant improvement in swimming performance (SMD = −0.34).
- No significant changes were observed in VO2max, HRmax, or VEmax.
- Greater benefits were found for 100 m and 200 m freestyle events and at simulated altitudes ≥3500 m.

## Abstract

To evaluate the effects of hypoxic interventions (HI) on swimming performance and physiological outcomes in competitive swimmers.

Systematic review and meta-analysis following PRISMA guidelines and registered in PROSPERO (CRD420251170303).

Seven databases were searched to identify controlled trials comparing hypoxic and normoxic training under identical conditions. Eleven studies (n = 182 swimmers) were included. Standardized mean differences (SMD) and 95% confidence intervals (CI) were calculated using a random-effects model. Subgroup analyses were performed by event distance and simulated altitude.

HI produced a small but significant improvement in swimming performance (SMD = −0.34, 95% CI [−0.62, −0.06], p = 0.02) with low heterogeneity (I2 = 30%). No significant changes were observed for VO2max, HRmax, or VEmax (all p > 0.05). Subgroup analyses indicated greater benefits for 100 m and 200 m freestyle and for interventions conducted at simulated altitudes ≥3500 m.

Hypoxic interventions yield meaningful yet modest enhancements in competitive swimming performance, likely through non-hematological adaptations such as improved muscle oxygen utilization and fatigue tolerance. Tailoring HI protocols to event-specific demands and sufficient hypoxic stimulus levels may optimize outcomes.

Registered on PROSPERO (registration number: CRD420251170303).

## Full-text entities

- **Diseases:** disease (MESH:D004194), fatigue (MESH:D005221), stroke (MESH:D020521), HI (MESH:D002534), Hypoxia (MESH:D000860)
- **Chemicals:** FTT (-), phosphagen (MESH:D010725), oxygen (MESH:D010100), FR (MESH:D005605)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

7 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12926167/full.md

## References

52 references — full list in the complete paper: https://tomesphere.com/paper/PMC12926167/full.md

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Source: https://tomesphere.com/paper/PMC12926167