# Editorial: Molecular and functional profiling in breast cancer: implications for hereditary and sporadic cases

**Authors:** Alessandra Virga, Michela Cortesi, Sara Bravaccini, Gianluca Tedaldi

PMC · DOI: 10.3389/fonc.2026.1773220 · Frontiers in Oncology · 2026-02-09

## Full-text entities

- **Genes:** BRCA1 (BRCA1 DNA repair associated) [NCBI Gene 672] {aka BRCAI, BRCC1, BROVCA1, FANCS, IRIS, PNCA4}, COL11A2 (collagen type XI alpha 2 chain) [NCBI Gene 1302] {aka DFNA13, DFNB53, FBCG2, HKE5, OSMEDA, OSMEDB}, SIGLEC7 (sialic acid binding Ig like lectin 7) [NCBI Gene 27036] {aka AIRM-1, AIRM1, CD328, CDw328, D-siglec, QA79}, APC (APC regulator of Wnt signaling pathway) [NCBI Gene 324] {aka BTPS2, DESMD, DP2, DP2.5, DP3, GS}
- **Diseases:** BC (MESH:D001943), triple-negative BC (MESH:D064726), ovarian cancer (MESH:D010051), hereditary breast and ovarian cancer (MESH:D061325), cytopenia (MESH:D006402), bone marrow (MESH:D001855), hereditary cancer syndromes (MESH:D009386), tumour (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]
- **Mutations:** c.5193 + 2dupT, I1307K

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12926152/full.md

## References

6 references — full list in the complete paper: https://tomesphere.com/paper/PMC12926152/full.md

---
Source: https://tomesphere.com/paper/PMC12926152