# Review: spinal shock, crossed extensor reflex, and mass reflex in dogs and cats—a literature review, clinical observations and considerations

**Authors:** Koen M. Santifort, Dakir Polidoro, Michelle Hermans, Agnieszka Olszewska, Adriana Kaczmarska, Federica Poli, Jos Bongers

PMC · DOI: 10.3389/fvets.2026.1703941 · Frontiers in Veterinary Science · 2026-02-09

## TL;DR

This review discusses spinal shock, crossed extensor reflex, and mass reflex in dogs and cats, focusing on their clinical relevance and underreported observations in veterinary neurology.

## Contribution

The paper highlights underreported clinical observations related to spinal reflexes in veterinary patients with acute spinal conditions.

## Key findings

- Asymmetrical spinal shock can occur in veterinary patients.
- Crossed extensor and mass reflexes are observed in patients with acute myelopathies.
- Pelvic limb crossed extensor reflex can appear with pathology not cranial to the lumbar intumescence.

## Abstract

The phenomena of spinal shock, crossed extensor reflex, and mass reflex are discussed to different extents in veterinary neurology textbooks, in literature on experimental animal models, and clinical reports on veterinary neurological patients. Aspects related to timing of onset of spinal pathology, their implications for neuroanatomical localizations, and their prognostic significance are clinically relevant. In this review article, the authors discuss and summarize the current literature and highlight collective observations in clinical veterinary neurology patients. Underreported observations emphasized in this article include the possibility of (1) asymmetrical/lateralized/unilateral spinal shock, (2) crossed extensor and mass reflexes in patients with (per-) acute myelopathies, (3) asymmetrical/lateralized/unilateral crossed extensor reflex, (4) mass reflexes observed in patients with (per-)acute myelopathies and concurrently with signs of spinal shock, and (5) a pelvic limb crossed extensor reflex in patients with pathology other than cranial to the lumbar intumescence.

## Full-text entities

- **Diseases:** Autonomic dysreflexia (MESH:D020211), contusion (MESH:D003288), lymphoma (MESH:D008223), -5 (MESH:D008232), acute intervertebral disc extrusion (MESH:D055959), depressed (MESH:D003866), areflexia (MESH:D000071699), epidural hemorrhage (MESH:D046748), luxation (MESH:D014084), paraparesis (MESH:D020335), necrosis (MESH:D009336), IVDE (MESH:C535531), hypertension (MESH:D006973), brain injury (MESH:D001930), ataxia (MESH:D001259), flaccid (MESH:D009123), gliosis (MESH:D005911), paresis (MESH:D010291), Loss of muscle tone (MESH:D009122), ischemic myelopathy (MESH:D020760), vertebral fracture (MESH:C535781), paralysis (MESH:D010243), spastic tetraparesis (MESH:C565722), T3-L3 (MESH:C537047), lower motor neuron disease (MESH:D016472), lesion (MESH:D009059), hyperesthesia (MESH:D006941), hemorrhages (MESH:D006470), ANNPE (MESH:C537927), intervertebral disc herniation (MESH:D007405), spastic tetraplegia (MESH:D011782), neck pain (MESH:D019547), cervical myelopathies (MESH:D002575), neurological disorder (MESH:D009461), Patellar hyperreflexia (MESH:D012021), acute myelopathies (MESH:D000208), SCI (MESH:D013119), paraplegia (MESH:D010264), myelopathies (MESH:D013118), pain (MESH:D010146), hereditary degenerative encephalopathy (MESH:D009386), trauma (MESH:D014947), dysphonia (MESH:D055154), spasticity (MESH:D009128), SS (MESH:D012769), loss of (MESH:D016388), Horner syndrome (MESH:D006732), thrombotic arteritis (MESH:D001167), and central nervous system injuries (MESH:D002493), edema (MESH:D004487), dyspnea (MESH:D004417), proprioceptive (MESH:D020886)
- **Chemicals:** glucose (MESH:D005947), glycine (MESH:D005998)
- **Species:** Equus caballus (domestic horse, species) [taxon 9796], Oryctolagus cuniculus (domestic rabbit, species) [taxon 9986], Cercopithecidae (monkey, family) [taxon 9527], Felis catus (cat, species) [taxon 9685], Homo sapiens (human, species) [taxon 9606], Angiostrongylus cantonensis (rat lungworm, species) [taxon 6313], Phoenicopterus roseus (flamingo, species) [taxon 435638], Canis lupus familiaris (dog, subspecies) [taxon 9615], Mus musculus (house mouse, species) [taxon 10090]

## Full text

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## Figures

9 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12926129/full.md

## References

88 references — full list in the complete paper: https://tomesphere.com/paper/PMC12926129/full.md

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Source: https://tomesphere.com/paper/PMC12926129