# Editorial: Advancing therapeutic strategies for relapsed/refractory acute lymphoblastic leukemia

**Authors:** Daniel Ebrahimi-Fakhari, Athanasios Tragiannidis

PMC · DOI: 10.3389/fmed.2026.1791558 · Frontiers in Medicine · 2026-02-09

## Full-text entities

- **Genes:** THBS1 (thrombospondin 1) [NCBI Gene 7057] {aka THBS, THBS-1, TSP, TSP-1, TSP1}, KMT2A (lysine methyltransferase 2A) [NCBI Gene 4297] {aka ALL-1, ALL1, CXXC7, GAS7, HRX, HTRX}, LTF (lactotransferrin) [NCBI Gene 4057] {aka GIG12, HEL110, HLF2, LF}
- **Diseases:** ALL (MESH:D054198), toxicity (MESH:D064420), leukemia (MESH:D007938), Ph+ disease (MESH:D010677), multiple myeloma (MESH:D009101), tumor (MESH:D009369), hematologic malignancies (MESH:D019337), B-ALL (MESH:D015452)
- **Chemicals:** VCA (-), azacitidine (MESH:D001374), venetoclax (MESH:C579720), chidamide (MESH:C547816), Olverembatinib (MESH:C579813)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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Source: https://tomesphere.com/paper/PMC12926092