# Autism Diagnostic Assessments for Gender-Diverse Individuals: A Modified Delphi Study of Clinician Experts in the Fields of Autism and Gender Diversity

**Authors:** Kate Cooper, Anna I.R. van der Miesen, Meng-Chuan Lai

PMC · DOI: 10.1016/j.jaacop.2025.10.001 · JAACAP Open · 2025-10-10

## TL;DR

Experts identified key considerations for autism assessments in gender-diverse individuals, highlighting how autism traits may intersect with gender diversity.

## Contribution

A modified Delphi study synthesized expert opinions on adapting autism diagnostic assessments for gender-diverse individuals.

## Key findings

- 37 key considerations were identified, categorized under general, diagnostic criteria, and practical aspects.
- Experts emphasized the intersection of autism features and gender diversity during assessments.
- The findings offer preliminary guidance for clinicians and researchers in this under-researched area.

## Abstract

There is limited evidence-based guidance about how autism diagnostic assessments should be conducted for gender-diverse people. This study aimed to integrate expert knowledge on key clinical considerations for these assessments.

A modified Delphi study was conducted. World experts in the field (N = 21) were invited to complete 2 rounds of surveys. Survey one collected open-text responses about key clinical considerations when conducting diagnostic assessments, structured around the DSM-5-TR criteria for autism, across age ranges. Experts were asked to rate the importance of each consideration they listed. A content analysis was conducted to synthesize and collate similar considerations, alongside descriptive statistics of importance ratings. Survey two presented the resulting considerations and mean importance ratings, with experts rerating their importance. Statements rated as at least “important” and that had an SD of less than 1.0 were reported.

Round one resulted in 65 individual statements, of which 37 met our definition for reporting. These statements, summarizing expert opinions, were categorized as being general considerations for assessments, linked to the DSM-5-TR autism criteria (A-E), or practical considerations for working with the gender-diverse population. They highlighted areas to be considered during assessments, such as ways in which the features of autism may intersect with gender diversity, and practical considerations for increasing comfort and engagement of gender-diverse individuals undergoing an autism assessment.

The summary of expert opinions provides preliminary considerations for clinicians working in this field and for researchers to use as hypotheses for empirical investigations.

Gender-diverse people are more likely to be diagnosed with autism or have autistic traits. In this study, the authors conducted surveys of 21 experts in conducting autism assessments in youth from around the world. The authors summarized expert opinion including general considerations for assessment, autism diagnostic criteria, and working with gender-diverse populations.

## Linked entities

- **Diseases:** autism (MONDO:0005260)

## Full-text entities

- **Diseases:** PTSD (MESH:D013313), learning disabilities (MESH:D007859), mental health problems (MESH:D000076082), Autism (MESH:D001321), dysphoria (MESH:D019052), anxiety (MESH:D001007), RRBIs (MESH:D001523), autism spectrum disorder (MESH:D000067877), trauma (MESH:D014947), personality disorders (MESH:D010554), social anxiety (MESH:D000072861), DSM-5-TR (MESH:D008232), OCD (MESH:D009771), depression (MESH:D003866), gender dysphoria (MESH:D000068116), ADHD (MESH:D001289), intellectual disabilities (MESH:D008607)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

53 references — full list in the complete paper: https://tomesphere.com/paper/PMC12925900/full.md

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Source: https://tomesphere.com/paper/PMC12925900