# When Stroke Mimics Peripheral Nerve Injury: A Case Report of Isolated Wrist Drop

**Authors:** Tai Anjuk Lama, Himal Karki, Kishor Khadka, Rabindara Raj Pandey, Bibek Rajbhandari

PMC · DOI: 10.31729/jnma.v64i293.9281 · JNMA: Journal of the Nepal Medical Association · 2026-01-31

## TL;DR

A rare case of wrist drop caused by a stroke highlights the importance of considering stroke in unusual neurological presentations.

## Contribution

This case report adds to the understanding of atypical stroke presentations with isolated wrist drop.

## Key findings

- Isolated wrist drop can be a rare manifestation of acute ischemic stroke.
- MRI confirmed a brain infarct despite a normal CT scan in this case.
- The patient improved with antiplatelet therapy, statins, and physiotherapy.

## Abstract

Isolated wrist drop as a presentation of stroke is uncommon and may pose a diagnostic dilemma. We present a case of a 65-year-old man with hypertension and diabetes who presented with sudden-onset weakness of the left hand and inability to extend fingers, without any other focal neurological deficits. Noncontrast computed tomography of the head was normal. However, diffusion-weighted magnetic resonance imaging of the brain revealed an acute ischemic infarct involving the right frontoparietal and occipital lobes. A diagnosis of isolated left-sided wrist drop secondary to acute ischemic stroke was made. The patient showed clinical improvement with antiplatelet and statin therapy, along with physiotherapy, on follow-up. Although rare, isolated wrist drop may be a manifestation of stroke, and clinicians must remain vigilant to avoid diagnostic delays and to administer appropriate treatment in a timely manner.

## Linked entities

- **Diseases:** diabetes (MONDO:0005015), stroke (MONDO:0005098)

## Full-text entities

- **Diseases:** motor deficits (MESH:D009461), fever (MESH:D005334), hand (MESH:D006230), vomiting (MESH:D014839), abnormal gait (MESH:D020233), ICH (MESH:D020300), nausea (MESH:D009325), Wrist Drop (MESH:D020425), Stroke (MESH:D020521), loss of consciousness (MESH:D014474), valvular vegetation (MESH:D006349), distal limb weakness (MESH:D018908), diabetes (MESH:D003920), cardioembolic (MESH:D000083262), facial deviation (MESH:D010262), inability to extend fingers (MESH:C535857), trauma (MESH:D014947), visual disturbances (MESH:D014786), Peripheral Nerve Injury (MESH:D059348), atherosclerotic plaques (MESH:D058226), cognitive impairment (MESH:D003072), Coma (MESH:D003128), ischemic attacks (MESH:D002546), abnormal body movements (MESH:D004409), Silent infarcts (MESH:D007238), sensory loss (MESH:C580162), artery-to-artery embolism (MESH:D012078), ischemic stroke (MESH:D002544), motor and sensory deficits (MESH:D001289), Distal monoparesis (MESH:D010291), dizziness (MESH:D004244), thrombus (MESH:D013927), loss of wrist and finger extension (MESH:D000092503), hypertension (MESH:D006973), LVH (MESH:D017379), atherosclerotic (MESH:D050197), smoker (MESH:C000719328)
- **Chemicals:** aspirin (MESH:D001241), antidiabetic medications (-), atorvastatin (MESH:D000069059)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12925831/full.md

## References

14 references — full list in the complete paper: https://tomesphere.com/paper/PMC12925831/full.md

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Source: https://tomesphere.com/paper/PMC12925831