# Pyogenic Granuloma in the Floor of Mouth: A Case Report

**Authors:** Mahesh Khadka, Rinky Nyachhyon, Shally Raina, Nisha Maharjan, Pragya Poudel, Subhekhysa Gyawali

PMC · DOI: 10.31729/jnma.v64i293.9288 · JNMA: Journal of the Nepal Medical Association · 2026-01-31

## TL;DR

This case report describes a rare occurrence of pyogenic granuloma in the mouth of a 43-year-old man.

## Contribution

The novelty lies in documenting a pyogenic granuloma in an uncommon location—the floor of the mouth—highlighting diagnostic challenges.

## Key findings

- Pyogenic granuloma was found in the floor of the mouth, a rare location for this condition.
- The case emphasizes the potential for diagnostic uncertainty due to the lesion's atypical presentation.

## Abstract

Pyogenic granuloma is a common benign, non-neoplastic inflammatory hyperplasia of keratinized tissue, typically arising in response to chronic irritation, trauma, or hormonal influences. Recently it has been classified under vascular tumor and termed as a lobular capillary hemangioma by International Society for the Study of Vascular Anomalies. It presents as a solitary, hemorrhagic, often pedunculated, nodules of variable size which typically appears most of the times in the gingiva. This report presents the case of a 43-year-old male with a pyogenic granuloma on the floor of the mouth. This rare location frequently leads to diagnostic uncertainty among clinicians.

## Linked entities

- **Diseases:** pyogenic granuloma (MONDO:0022096)

## Full-text entities

- **Diseases:** Pyogenic Granuloma (MESH:D017789), Giant Cell Granuloma (MESH:D006101), Ossifying Fibroma (MESH:D018214), traumatic fibroma (MESH:D005350), infectious (MESH:D003141), Vascular Anomalies (MESH:D020785), hyperplasia (MESH:D006965), inflammatory (MESH:D007249), injuries (MESH:D014947), fibrosis (MESH:D005355), Swelling (MESH:D004487), irritation (MESH:D001523), calcification (MESH:D002114), vascular tumor (MESH:D009369), cancer phobia (MESH:C000719212), pregnancy tumor (MESH:D011252), bleeding (MESH:D006470), oral mucosal lesion (MESH:D009059), Squamous Cell Carcinoma (MESH:D002294)
- **Chemicals:** Hematoxylin (MESH:D006416), eosin (MESH:D004801)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12925828/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12925828/full.md

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Source: https://tomesphere.com/paper/PMC12925828