# Clinical Profile of Ectopic Pregnancy in a Tertiary Care Center: A Five-Year Retrospective Study

**Authors:** Deepa Chudal, Agya Shrestha, Rojina Manandhar, Santosh Thakur, Deepak Kharel, Usha Shrestha, Binita Basnet

PMC · DOI: 10.31729/jnma.v64i293.9296 · JNMA: Journal of the Nepal Medical Association · 2026-01-31

## TL;DR

This study examines the clinical characteristics and management of ectopic pregnancies over five years at a hospital in Nepal.

## Contribution

The study provides a detailed clinical profile of ectopic pregnancies in a Nepalese tertiary care center.

## Key findings

- Abdominal pain was the most common symptom in 71.42% of cases.
- Tubal rupture occurred in 88.09% of patients, with the ampullary region being the most frequent site.
- Laparoscopic unilateral salpingectomy was the most common surgical procedure used.

## Abstract

Ectopic pregnancy is a major cause of maternal morbidity and mortality in the first trimester. Delayed diagnosis often results in rupture, leading to life-threatening complications and adverse fertility outcomes. This study aimed to evaluate the incidence, risk factors, clinical presentation, and management of ectopic pregnancy in a tertiary care center in Nepal.

A five-year retrospective observational study was conducted at Nepal Police Hospital, Kathmandu from March 1, 2020, to February 28, 2025. All confirmed cases of ectopic pregnancy were included. Data on socio-demographics, risk factors, clinical features, operative findings, and management were collected from hospital records. Descriptive statistics were applied.

Among 1,760 live births, 42 (2.38%) cases of ectopic pregnancy were identified. The mean age of the patients was 29.69±5.41 years, with the majority of cases occurring in women aged 20-35 years. Abdominal pain was the most common presenting symptom, reported in 30 (71.42%) patients. A history of abortion was the leading risk factor, noted in 14 (33.3%) cases. Tubal rupture was observed in 37 (88.09%) patients, and the ampullary region was the most frequent site, involved in 38 (90.47%) cases. All patients underwent surgical management, with laparoscopic unilateral salpingectomy being the most commonly performed procedure in 36 (85.71%) cases.

The most common presenting symptom was abdominal pain in patients in the age group of 31-35 years. Most patient presented with ruptured ectopics.

## Linked entities

- **Diseases:** ectopic pregnancy (MONDO:0000755)

## Full-text entities

- **Diseases:** rupture (MESH:D012421), adnexal masses (MESH:D000291), Abdominal pain (MESH:D015746), Ectopic Pregnancy (MESH:D011271), pain (MESH:D010146), tubal damage (MESH:D005184), amenorrhea (MESH:D000568), bleeding (MESH:D006470), pelvic inflammatory disease (MESH:D000292), abortion (MESH:D000026), vaginal bleeding (MESH:D014592), death (MESH:D003643), maternal (MESH:D000079262), pelvic infections (MESH:D034161)
- **Chemicals:** methotrexate (MESH:D008727)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC12925827/full.md

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Source: https://tomesphere.com/paper/PMC12925827