# Buccal dantrolene for rapid systemic delivery: A novel antiarrhythmic approach

**Authors:** Sofiane Ouerd, Praloy Chakraborty, Stéphane Massé, Patrick F.H. Lai, Eric X. Chen, Eitan Amir, Nigel deGruyther, Kumaraswamy Nanthakumar

PMC · DOI: 10.1016/j.hroo.2025.11.012 · Heart Rhythm O2 · 2025-11-25

## Full-text entities

- **Genes:** RYR2 (ryanodine receptor 2) [NCBI Gene 396856]
- **Diseases:** arrhythmia (MESH:D001145), heart failure (MESH:D006333), bleeding (MESH:D006470), calcium dysregulation (MESH:D002128), cardiac emergencies (MESH:D006331), hyperemia (MESH:D006940)
- **Chemicals:** azumolene (MESH:C061387), water (MESH:D014867), Dantrolene (MESH:D003620)
- **Species:** Canis lupus familiaris (dog, subspecies) [taxon 9615], Sus scrofa (pig, species) [taxon 9823]

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## References

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Source: https://tomesphere.com/paper/PMC12925744