Surgeon seniority and performance in breast-conserving surgery for non-palpable lesions: evidence from a multicenter study

TL;DR

This study finds that surgeon experience does not significantly affect outcomes in breast-conserving surgery for non-palpable lesions when performed under supervision.

Contribution

The study is one of the few to directly examine surgeon seniority's impact on surgical performance in BCS for non-palpable lesions.

Findings

Surgeon seniority did not significantly affect margin status or complication rates in BCS for non-palpable lesions.

Residents achieved better calculated resection ratios with ROLL procedures but had longer operative times.

ROLL and MSL localization methods may help mitigate the effects of surgical inexperience.

Abstract

Breast-conserving surgery (BCS) for non-palpable lesions is technically demanding, often performed by surgical trainees under supervision. Despite extensive literature evaluating localization techniques, only few studies have directly examined the role of surgeon seniority in determining surgical performance in this specific setting.

We conducted a retrospective multicenter analysis (LOCALIZATION01 study, NCT05942105) including 3,195 patients who underwent BCS for non-palpable breast lesions between 2016 and 2024 across 12 Breast Units. Four localization techniques were used: wire-guided (WGL), radioguided occult lesion localization (ROLL), magnetic seed localization (MSL), carbon localization (CL). Outcomes included margin status, calculated resection ratio (CRR), operative time, and complications, stratified by surgeon seniority (attending vs resident).

Most procedures were performed by attending surgeons (89.3%, n = 2,855) compared to residents (10.7%, n = 340). Margin positivity rates didn't differ significantly across localization techniques (e.g., ROLL 3.7% vs 2.3%, p = 0.30; MSL 9.4% vs 4.4%, p = 0.11, WGL 2.7% vs 5.9 p = 0.16, CL 0% vs 9.6% p = 0.10). Residents achieved better CRR in ROLL procedures (2.0, IQR 3, [1-47] vs 2.8, IQR 5, [1-78], p = 0.006), but had longer operative times, particularly with SLNB (e.g., MSL 60 min, IQR 31, [37-98] vs 55 min, IQR 20, [18−180], p = 0.02). Complication rates were low and comparable between groups.

In a supervised setting, surgeon seniority doesn't significantly impact margin status, complication rates, or overall oncologic safety in BCS for non-palpable breast lesions. Localization methods with high reproducibility, such as ROLL and MSL, may mitigate the influence of surgical inexperience. These findings support the safe involvement of trainees in BCS under adequate supervision.

•Non-palpable breast lesions requires accurate localization methods.•Surgeon seniority did not significantly affect margins, complications, or safety.•Residents achieved better CRR with ROLL but had longer operative times overall.•ROLL and MSL may offset inexperience, supporting safe trainee involvement.

Non-palpable breast lesions requires accurate localization methods.

Surgeon seniority did not significantly affect margins, complications, or safety.

Residents achieved better CRR with ROLL but had longer operative times overall.

ROLL and MSL may offset inexperience, supporting safe trainee involvement.