# Decodability, sensitivity, and criticality measured through single-neuron perturbations

**Authors:** Matthew Farrell, Taro Toyoizumi

PMC · DOI: 10.1038/s41467-026-69121-9 · 2026-02-13

## TL;DR

The paper discusses how single-neuron spikes affect the surrounding brain network and reveal complex patterns of neural computation.

## Contribution

The study introduces a novel approach to analyze neural computation through decodability, sensitivity, and criticality using single-neuron perturbations.

## Key findings

- Single-neuron spikes influence the surrounding cortical network dynamics.
- Local perturbations reveal multi-faceted signatures of critical neural computation.

## Abstract

This comment highlights a new study by Ribeiro et al.1 which investigates how single-neuron spikes influence the surrounding cortical network in vivo. By comparing induced and background spikes through the lenses of decodability, sensitivity, and criticality, this work highlights how local perturbations interact with ongoing network dynamics to reveal multi-faceted signatures of critical neural computation.

## Full-text entities

- **Chemicals:** spike (MESH:C010346)

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12923575/full.md

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Source: https://tomesphere.com/paper/PMC12923575