# Hydrogen Peroxide Inhalation During Dental Whitening Leading to Massive Hemoptysis and Tumor-Like Endobronchial Obstruction: A Case Report

**Authors:** Redouene Sid Ahmed Benazzouz, Massinissa Benyagoub, Nassim Nedjar

PMC · DOI: 10.7759/cureus.102009 · Cureus · 2026-01-21

## TL;DR

A woman developed severe lung issues after inhaling hydrogen peroxide during a dental whitening procedure, leading to coughing, bleeding, and lung collapse.

## Contribution

This case report highlights a rare but severe complication of high-concentration hydrogen peroxide use in dental procedures.

## Key findings

- Hydrogen peroxide inhalation caused airway injury, leading to hemoptysis and lung atelectasis.
- The condition resolved after one month without further intervention.
- Bronchoscopy was complicated by mucus expectoration and could not be completed.

## Abstract

Hydrogen peroxide (H₂O₂) is widely used in dental whitening and is generally considered safe when applied under professional supervision. However, accidental aspiration may cause unexpected airway complications.

A 55-year-old North African woman presented with massive hemoptysis, preceded by a 3-month history of persistent dry cough and an earlier minor hemoptysis episode. Symptoms had begun shortly after a dental whitening procedure using 35% H₂O₂, complicated by intense pharyngeal pain, ulcerative lesions, and severe coughing. Chest imaging showed complete left lower lobe atelectasis due to an intraluminal soft-tissue lesion, with associated parenchymal consolidation. Flexible bronchoscopy was attempted but interrupted due to complications, after which the patient expectorated thick mucus. Follow-up imaging one month later demonstrated complete resolution of the lesion and full lung re-expansion.

This case highlights the potential for severe airway injury following dental use of high-concentration H₂O₂. Awareness of such iatrogenic exposures is essential when evaluating unexplained hemoptysis and atelectasis.

## Linked entities

- **Chemicals:** Hydrogen peroxide (PubChem CID 784)
- **Species:** Homo sapiens (taxon 9606)

## Full-text entities

- **Genes:** CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}
- **Diseases:** diminished breath sounds (MESH:D012135), mucosal abnormalities (MESH:D052016), ciliary dysfunction (MESH:D002925), Endobronchial tuberculosis (MESH:D014376), bronchial lesions (MESH:D001982), edentulism (MESH:D007575), atelectasis (MESH:D001261), hypertensive (MESH:D006973), pharyngeal pain (MESH:D010612), coagulation disorder (MESH:D001778), cardiovascular disease (MESH:D002318), ulceration (MESH:D014456), cough (MESH:D003371), Endobronchial lesions (MESH:D009059), bleeding (MESH:D006470), respiratory (MESH:D012131), lymphadenopathy (MESH:D008206), pleural effusion (MESH:D010996), Hemoptysis (MESH:D006469), pneumonitis (MESH:D011014), airway disease (MESH:D029424), vascular malformation (MESH:D054079), pulmonary embolism (MESH:D011655), airway injury (MESH:D000402), pulmonary dysfunction (MESH:D011660), hypoxemia (MESH:D000860), endobronchial masses (MESH:C536030), inflammation (MESH:D007249), complications (MESH:D008107), bronchogenic carcinoma (MESH:D002283), vascular lesion (MESH:D014652), Tumor (MESH:D009369), cyanosis (MESH:D003490), mucosal irritation (MESH:D001523), dyspnea (MESH:D004417), pulmonary injury (MESH:D055370), pulmonary edema (MESH:D011654)
- **Chemicals:** H2O2 (MESH:D006861), fumes (-), peroxide (MESH:D010545), etamsylate (MESH:D004979)
- **Species:** Mycobacterium tuberculosis (species) [taxon 1773], Homo sapiens (human, species) [taxon 9606], Mycobacteriales (order) [taxon 85007]

## Full text

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## Figures

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## References

6 references — full list in the complete paper: https://tomesphere.com/paper/PMC12923172/full.md

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Source: https://tomesphere.com/paper/PMC12923172