# Association of anxiety and depression with cognitive challenges in children in Bangladesh

**Authors:** M. Iftakhar Alam, Mohaimen Mansur

PMC · DOI: 10.1371/journal.pone.0343489 · PLOS One · 2026-02-20

## TL;DR

This study found that children in Bangladesh with anxiety or depression are more likely to have difficulties with communication, learning, remembering, or concentrating.

## Contribution

The study establishes a strong association between anxiety/depression and cognitive challenges in children in Bangladesh, while accounting for sociodemographic factors.

## Key findings

- Children with anxiety or depression had significantly higher odds of cognitive challenges (OR = 7.82).
- Males were 30% more likely to have cognitive challenges than females.
- Children of mothers with secondary education had reduced odds of cognitive challenges (OR = 0.80).

## Abstract

This study primarily investigated the association of anxiety or depression (AD) with communication, learning, remembering, or concentrating (CLRC) difficulties in children aged 5-17 years in Bangladesh. Data were taken from the 2019 Bangladesh Multiple Indicator Cluster Survey (MICS). Random intercept binary logistic regression model was used to assess the association between CLRC and AD, after controlling sex, age, division, maternal education, maternal functional difficulty, and wealth index. Children with AD difficulties had significantly higher odds of CLRC (OR = 7.82; 95% CI: 6.29–9.73). Males were 30% more likely to have CLRC than females (OR = 1.30; 95% CI: 1.12–1.51). Compared with children living in Barishal-the reference administrative region-children residing in several other divisions had significantly lower odds of experiencing CLRC. Children of mothers with secondary education had reduced odds of CLRC (OR = 0.80), while those whose mothers had functional difficulties had higher odds (OR = 3.00). To conclude, AD difficulties is strongly associated with CLRC, alongside other factors like sex, geographic location, maternal education, and wealth. Addressing these factors is crucial for reducing CLRC difficulties in children.

## Linked entities

- **Diseases:** anxiety (MONDO:0005618), depression (MONDO:0002050)

## Full-text entities

- **Diseases:** mental health (OMIM:603663), ADHD (MESH:D001289), depression (MESH:D003866), impairments in attention, memory, and learning (MESH:D008569), CLRC (MESH:D003147), emotional or internalizing disorders (MESH:D000082122), Cognitive difficulties (MESH:D003072), neurodevelopmental conditions (MESH:D020763), AD (MESH:D001007), Learning difficulties (MESH:D007859), functional (MESH:D003291), difficulties (MESH:D051346), Anxiety disorders (MESH:D001008)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

11 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12923135/full.md

## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC12923135/full.md

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Source: https://tomesphere.com/paper/PMC12923135