# Financial burden of severe childhood illness on households in Lao People’s Democratic Republic: A prospective cohort study

**Authors:** Alicia Quach, Mayfong Mayxay, Laddaphone Bounvilay, Amphaivanh Thammavong, Toukta Bounkhoun, Chom Phaiphichit, Nar Kingkeooudom, Sommanikhone Phangmanixay, Phouthalavanh Souvannasing, Elizabeth A. Ashley, Cattram Nguyen, Natalie Carvalho, Fiona M. Russell

PMC · DOI: 10.1371/journal.pgph.0004783 · PLOS Global Public Health · 2026-02-20

## TL;DR

This study examines how severe childhood illness affects household finances in Laos, comparing hospitals with and without health insurance coverage.

## Contribution

The study provides new empirical evidence on financial burdens of severe childhood illness in Laos, comparing hospitals with and without national health insurance.

## Key findings

- Households at the hospital without NHI faced higher out-of-pocket costs and higher rates of catastrophic health expenditure.
- Impoverishment was significantly higher at the hospital without NHI compared to the one with NHI.
- Disadvantaged households, especially those with no maternal formal education, faced a higher risk of catastrophic health expenditure.

## Abstract

Lao People’s Democratic Republic (PDR) introduced a National Health Insurance (NHI) scheme in 2016 to all provinces except Vientiane Capital City. We describe the financial impact on households related to treatment of severe childhood illness at a hospital covered by NHI, and one without NHI. We conducted a prospective cohort study (2022–2024) in Lao PDR of children aged one month to <15 years admitted with severe illness at Salavan Provincial Hospital (SPH) with NHI, and National Children’s Hospital (NCH) without NHI, with two-month follow-up post-discharge. Illness-related direct and indirect costs were collected. We calculated household out-of-pocket (OOP) costs, impoverishment and catastrophic health expenditure (CHE, > 10% annual household expenditure) rates and analysed relative risk (RR) of CHE by socioeconomic status. 200 participants were recruited from each hospital with demographic differences observed between hospitals in urban residence (NCH 87.0%, SPH 14.5%), maternal education (primary level: NCH 95.9%, SPH 76.3%) and wealth status (wealthiest quintile: NCH 79.0%, SPH 20.5%). Median household OOP costs were higher at NCH (USD290.6 [IQR 206.9–422.9]) compared to SPH (USD92.4 [IQR 56.3–52.9]). Impoverishment at two months post-discharge was 0.5% (95%CI 0.0-3.0) at NCH and 10.2% (95%CI 6.2-15.4) at SPH. CHE rates were 34.5% (95%CI 27.9-41.1) at NCH and 26.0% (95%CI 19.9-32.1) at SPH, with higher RR in the poorest versus wealthiest households (NCH: RR 6.6, 95%CI 4.5-9.5; SPH: RR 4.9, 95%CI 1.7-13.7) and households with no formal maternal education versus secondary education (NCH: RR 2.6, 95%CI 1.2-5.5; SPH: RR 4.6, 95%CI 1.92-11.1). Direct medical costs were lower at the provincial hospital where NHI is available, but total OOP costs and CHE rates were high at both hospitals, particularly among disadvantaged households. Additional interventions are required to prevent severe illness and provide financial protection for socioeconomically disadvantaged groups to reduce health-related economic burden on households in Lao PDR.

## Full-text entities

- **Diseases:** obstructed (MESH:D000402), convulsions (MESH:D012640), respiratory distress (MESH:D012128), coma (MESH:D003128), illness (MESH:D002908), infectious diseases (MESH:D003141), Pneumonia (MESH:D011014), COVID-19 (MESH:D000086382), cyanosis (MESH:D003490), dehydration (MESH:D003681), OOP (MESH:D005888), shock (MESH:D012769), respiratory tract infection (MESH:D012141), NCH (MESH:D003428), CHE (MESH:D002388), death (MESH:D003643), gastroenteritis (MESH:D005759)
- **Chemicals:** oxygen (MESH:D010100)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

48 references — full list in the complete paper: https://tomesphere.com/paper/PMC12923058/full.md

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Source: https://tomesphere.com/paper/PMC12923058