# Awareness Level of Herpes Zoster Infection Among the Residents of Jeddah, Saudi Arabia

**Authors:** Reem A Algarni, Lama A Rammal, Amira M Marei, Anfal Saber, Raghad Alhajrasi, Laura Althuniyyan, Mawdah Hindi, Shahad Alzahrani

PMC · DOI: 10.7759/cureus.101941 · Cureus · 2026-01-20

## TL;DR

This study assesses how much people in Jeddah, Saudi Arabia know about herpes zoster and its vaccine, finding moderate awareness but significant gaps.

## Contribution

The study provides new data on herpes zoster awareness and vaccine knowledge in Saudi Arabia, highlighting misconceptions and key factors influencing vaccination.

## Key findings

- 85.1% of participants were aware of herpes zoster, but only 34.2% knew about its vaccine.
- Participants with a family history of herpes zoster were more likely to be vaccinated (OR: 4.2).
- Awareness and knowledge varied, with notable misconceptions observed.

## Abstract

Introduction: Herpes zoster (HZ), also known as shingles, is a viral infection caused by the reactivation of the varicella-zoster virus. Awareness and knowledge of HZ and its associated complications vary across countries. Limited data are available on the awareness and knowledge of HZ among the general population in Saudi Arabia. Therefore, this study aims to measure awareness of HZ infection and its vaccine among the citizens of Jeddah, Saudi Arabia.

Methods: An online questionnaire was distributed to the citizens of Jeddah, Saudi Arabia, to assess their awareness and knowledge of HZ. The questionnaire included demographic characteristics, awareness of HZ and its vaccine, and knowledge about both HZ and the HZ vaccine. Descriptive statistics and logistic regression analysis were used to analyze the data.

Results: A total of 557 valid responses were included in the analysis. The majority were female participants (79%) and Saudi nationals (94.8%). The awareness level of HZ was high, with 85.1% of participants reporting having heard of it. However, only 34.2% were aware of the HZ vaccine. The knowledge level regarding HZ and its vaccine varied, with some misconceptions observed. Factors associated with HZ vaccination included age, family history of HZ, and awareness of HZ. Participants with a family history of HZ had higher odds of vaccination (OR: 4.2, p = 0.002).

Conclusion: This study revealed moderate awareness and knowledge of HZ and its vaccine among citizens of Jeddah, Saudi Arabia. Improving knowledge about HZ and its vaccine can contribute to the prevention and management of this viral infection.

## Linked entities

- **Diseases:** Herpes zoster (MONDO:0005609)

## Full-text entities

- **Diseases:** bacterial infection (MESH:D001424), HZ (MESH:D006562), herpes (MESH:C536395), Abnormal skin (MESH:D012868), neuropathy (MESH:D009422), blisters (MESH:D001768), neurological damage (MESH:D020196), Hypertension (MESH:D006973), death (MESH:D003643), viral infection (MESH:D014777), cardiovascular disease (MESH:D002318), encephalitis (MESH:D004660), gastrointestinal diseases (MESH:D005767), vision, or hearing loss (MESH:D054062), rash (MESH:D005076), hair loss (MESH:D000505), autoimmune diseases (MESH:D001327), PHN (MESH:D051474), blindness (MESH:D001766), nerve palsy (MESH:D003389), flu (MESH:D007251), pain (MESH:D010146), diabetes mellitus (MESH:D003920), chickenpox (MESH:D002644)
- **Chemicals:** SHINGRIX (-)
- **Species:** Homo sapiens (human, species) [taxon 9606], Human alphaherpesvirus 3 (Varicella-zoster virus, no rank) [taxon 10335]

## Full text

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## References

21 references — full list in the complete paper: https://tomesphere.com/paper/PMC12922722/full.md

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Source: https://tomesphere.com/paper/PMC12922722