# ST-Elevation Myocardial Infarction Systems of Care in Africa: A Scoping Review

**Authors:** Albertus Johannes Pool, Pierre Christo Smit, Helen Slabber, Willem Stassen

PMC · DOI: 10.5334/gh.1524 · Global Heart · 2026-02-17

## TL;DR

This review explores the challenges in treating heart attacks in Africa, highlighting gaps in healthcare systems and suggesting improvements for better patient outcomes.

## Contribution

The study provides a comprehensive overview of STEMI systems of care in Africa, identifying key barriers and facilitators for implementation.

## Key findings

- STEMI patients in Africa are younger and face late presentation and inadequate healthcare insurance.
- There is a lack of emergency medical services and PCI facilities, leading to delayed reperfusion times.
- Deficiencies in ECG, telemetry, and guideline adherence suggest a need for clinical education and system improvements.

## Abstract

ST-elevation myocardial infarction (STEMI) is a life-threatening, time-sensitive emergency. Cardiovascular diseases, including STEMI, are increasing on the African continent. Improving optimal outcomes for these patients requires a system-wide approach as the existing literature is unclear.

To describe and summarise the African literature on STEMI Systems of Care (STEMI SOC).

This scoping review was designed following the PRISMA-ScR guidelines. An a priori search strategy was applied to EbscoHost, PubMed, and Google Scholar databases.

A total of 671 articles were identified. Following the exclusion of 619 articles, 52 articles were eligible for inclusion. STEMI patients in Africa are generally younger than their Western counterparts, present late to healthcare facilities, have insufficient healthcare insurance, and are non-adherent to discharge medication. Emergency medical services are lacking, there is a shortage of percutaneous coronary intervention (PCI) facilities, and emergency departments are disorganised. STEMI reperfusion times are delayed, data collection and quality assurance initiatives are inadequate, and STEMI referral networks and registries are underdeveloped. In addition, there is a deficiency of ECG and telemetry, a shortage of healthcare workers, a lack of adherence to guideline-recommended therapy, and a perceived hesitancy of medical personnel to administer fibrinolytics. These findings suggest a need for more clinical education.

A myriad of barriers, as well as potential facilitators in the implementation of these networks, have been reported in this scoping review. The coordination and introduction of a STEMI SOC in African settings potentially holds great advantages, as has been witnessed in other low- and middle-income countries (LMICs) and high-income countries (HICs).

## Linked entities

- **Diseases:** ST-elevation myocardial infarction (MONDO:0041656)

## Full-text entities

- **Genes:** FASTK (Fas activated serine/threonine kinase) [NCBI Gene 10922] {aka FAST}
- **Diseases:** PPCI (MESH:D003323), communicable, maternal, perinatal, and nutritional diseases (MESH:D003141), re-infarction (MESH:D007238), heart failure (MESH:D006333), FMC (MESH:D061219), IHDs (MESH:D006331), CVD (MESH:D002318), acute myocardial infarction (MESH:D009203), death (MESH:D003643), ST-Elevation Myocardial Infarction (MESH:D000072657), ACS (MESH:D054058)
- **Chemicals:** morphine (MESH:D009020), BMS (-), clopidogrel (MESH:D000077144), aspirin (MESH:D001241), salt (MESH:D012492), nitrates (MESH:D009566)
- **Species:** Homo sapiens (human, species) [taxon 9606], Human immunodeficiency virus 1 (no rank) [taxon 11676]

## Full text

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## Figures

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## References

89 references — full list in the complete paper: https://tomesphere.com/paper/PMC12922679/full.md

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Source: https://tomesphere.com/paper/PMC12922679