# Prevention as a Pillar of Communicable Disease Control: Strategies for Equity, Surveillance, and One Health Integration

**Authors:** Giovanni Genovese, Caterina Elisabetta Rizzo, Linda Bartucciotto, Serena Maria Calderone, Francesco Loddo, Francesco Leonforte, Antonio Mistretta, Raffaele Squeri, Cristina Genovese

PMC · DOI: 10.3390/epidemiologia7010019 · Epidemiologia · 2026-02-03

## TL;DR

The paper argues that prevention is key to controlling communicable diseases, emphasizing equity, surveillance, and integrating human, animal, and environmental health.

## Contribution

It highlights the integration of AI, big data, genomics, and the One Health approach as novel strategies for disease prevention.

## Key findings

- Advanced technologies like AI and genomics are transforming infectious disease management.
- The One Health approach is critical for addressing zoonoses and antimicrobial resistance.
- Equitable financing and global cooperation are essential for effective disease prevention.

## Abstract

Global health faces unprecedented challenges driven by communicable diseases, which are increasingly amplified by persistent health inequities, the impact of climate change, and the speed of emerging crises. Prevention is not merely a component but the foundational strategy for an effective, sustainable, and fiscally responsible public health response. This paper delves into the pivotal role of core prevention levers: robust vaccination programs, stringent hygiene standards, advanced epidemiological surveillance, and targeted health education. We detail how contemporary technological advancements, including Artificial Intelligence (AI), big data analytics, and genomics, are fundamentally reshaping infectious disease management, enabling superior predictive capabilities, faster early warning systems, and personalized prevention models. Furthermore, we thoroughly examine the imperative of integrating the One Health approach, which formally recognizes the close, interdependent links between human, animal, and environmental health as critical for combating complex threats like zoonoses and Antimicrobial Resistance (AMR). Despite significant scientific progress, persistent socio-economic disparities, the pervasive influence of health-related misinformation (infodemics), and structural weaknesses in global preparedness underscore the urgent need for decisive international cooperation and equitable financing models. We conclude that only through integrated, multidisciplinary, and resource-equitable strategies can the global community ensure effective prevention, mitigate severe socio-economic disruption, and successfully build resilient healthcare systems capable of withstanding future global health threats.

## Linked entities

- **Diseases:** zoonoses (MONDO:0025481)

## Full-text entities

- **Diseases:** anxiety (MESH:D001007), COVID-19 (MESH:D000086382), AMR (MESH:D060467), influenza (MESH:D007251), viral hepatitis (MESH:D014777), injury to (MESH:D014947), avian influenza (MESH:D005585), dysentery (MESH:D004403), Ebola (MESH:D019142), tetanus (MESH:D013746), pertussis (MESH:D014917), Communicable (MESH:D003141), HIV/AIDS (MESH:D015658), malaria (MESH:D008288), diphtheria (MESH:D004165), zoonotic diseases (MESH:D015047), tuberculosis (MESH:D014376), measles (MESH:D008457), cholera (MESH:D002771), depression (MESH:D003866)
- **Species:** Homo sapiens (human, species) [taxon 9606], Ebola virus (no rank) [taxon 1570291], Bacteriophage sp. (species) [taxon 38018], Severe acute respiratory syndrome coronavirus 2 (no rank) [taxon 2697049]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12921955/full.md

## References

73 references — full list in the complete paper: https://tomesphere.com/paper/PMC12921955/full.md

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Source: https://tomesphere.com/paper/PMC12921955