# The Role of Serial Fetal Echocardiography in Postnatal Surgical Decision-Making for Borderline Left Ventricle: A Case Report

**Authors:** Andreea Cerghit-Paler, Dorottya Gabor-Miklosi, Iolanda Muntean, George-Andrei Crauciuc, Daniela Toma, Laura Beligan, Liliana Gozar

PMC · DOI: 10.3390/pediatric18010018 · Pediatric Reports · 2026-02-02

## TL;DR

Serial fetal echocardiography helped guide surgical decisions for a baby with a borderline left ventricle, leading to successful biventricular repair and good outcomes.

## Contribution

Demonstrates how serial fetal echocardiography can inform postnatal surgical strategies for borderline left ventricle cases.

## Key findings

- Serial fetal echocardiography showed stable left ventricular dimensions and preserved systolic function.
- Postnatal biventricular repair led to favorable outcomes with normalized valve z-scores and preserved ventricular function.
- Mid-term follow-up showed no evidence of myocardial fibrosis and good left ventricular performance.

## Abstract

Background: Borderline left ventricle represents a heterogeneous spectrum of congenital heart disease for which accurate prediction of suitability for biventricular versus univentricular circulation is often difficult. Serial fetal echocardiography may provide dynamic information to support postnatal decision-making. Case Presentation: We report the case of a fetus diagnosed at 32 weeks’ gestation with a borderline left ventricle, ventricular disproportion, hypoplastic left-sided structures, ductal-dependent systemic circulation, and a non-restrictive ostium secundum atrial septal defect. Serial fetal echocardiographic evaluations demonstrated stable left ventricular dimensions, preserved systolic function, impaired diastolic relaxation, and absence of endomyocardial fibroelastosis. Postnatal echocardiography confirmed hypoplastic aortic arch and coarctation. Following multidisciplinary evaluation, a biventricular repair strategy was selected. At 14 days of life, the patient underwent aortic arch reconstruction and partial atrial septal defect closure with preservation of a small therapeutic interatrial communication. Postoperative evolution was favorable, with progressive left ventricular growth and preserved function. At 2-year follow-up, echocardiography showed normalized mitral and aortic valve z-scores, good left ventricular systolic performance, and no evidence of myocardial fibrosis. Conclusions: This case highlights the value of serial fetal echocardiography in guiding individualized management of borderline left ventricle. Careful assessment of ventricular function and atrial septal physiology may support selection of a biventricular strategy in selected patients and contribute to favorable mid-term outcomes.

## Linked entities

- **Diseases:** congenital heart disease (MONDO:0005453)

## Full-text entities

- **Genes:** PGLS (6-phosphogluconolactonase) [NCBI Gene 25796] {aka 6PGL, HEL-S-304}
- **Diseases:** dilation (MESH:D002311), Cardiovascular Disease (MESH:D002318), hypertrophy (MESH:D006984), patent ductus arteriosus (MESH:D004374), congenital heart disease (MESH:D006330), endomyocardial fibroelastosis (MESH:D004695), extracardiac malformations (MESH:C564254), bicuspid aortic valve (MESH:D000082882), pulmonary hypertension (MESH:D006976), heart failure (MESH:D006333), atrial dilation (MESH:C563984), Borderline left ventricle (MESH:D020257), hypoplastic ascending aorta (MESH:D000094630), hypoplastic (MESH:D000741), systolic dysfunction (MESH:D006331), aortic coarctation (MESH:D001017), myocardial disease (MESH:D004194), injury to (MESH:D014947), hypoplasia (MESH:D000080344), ASD (MESH:D006344), hypoplastic aortic arch (MESH:D001015), myocardial fibrosis (MESH:D005355), hypoplasia of the aortic isthmus (MESH:D001018), chambers (MESH:C535679), Left ventricular diastolic dysfunction (MESH:D018487), ventricular dilation (MESH:C566255), aortic stenosis (MESH:D001024), ventricular disproportion (MESH:D020914), mitral or aortic stenosis (MESH:D008946), hypoplastic ventricles (MESH:D002551), pulmonary venous congestion (MESH:D006940), stroke (MESH:D020521)
- **Chemicals:** prostaglandin E1 (MESH:D000527), oxygen (MESH:D010100)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12921919/full.md

## References

35 references — full list in the complete paper: https://tomesphere.com/paper/PMC12921919/full.md

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Source: https://tomesphere.com/paper/PMC12921919