# Bilateral Thalamic Stroke Following Cardiac Arrest Due to Massive Saddle Pulmonary Embolism

**Authors:** Abay Gobezie, Kristin N Slater, Haregua Zenebe, Mahburbur Sumon

PMC · DOI: 10.7759/cureus.101964 · Cureus · 2026-01-21

## TL;DR

A rare case of bilateral thalamic stroke occurred after a massive pulmonary embolism caused cardiac arrest.

## Contribution

This case report documents the rare combination of bilateral thalamic stroke and massive saddle pulmonary embolism.

## Key findings

- Bilateral thalamic stroke can result from global cerebral hypoperfusion after cardiac arrest.
- Massive saddle pulmonary embolism is a dangerous cause of cardiopulmonary compromise.
- Such combined events are extremely rare and underreported in medical literature.

## Abstract

Bilateral thalamic infarctions are rare, but can be seen in patients experiencing occlusion or hypoperfusion. Saddle emboli can be very dangerous, leading to cardiac arrest. The occurrence of both in a single patient is an incredibly rare and dangerous entity, infrequently found in the literature. We present a case of a bilateral thalamic stroke in a 55-year-old male who experienced cardiac arrest secondary to a massive saddle pulmonary embolism. This case highlights the rare occurrence of bilateral thalamic infarction in the context of global cerebral hypoperfusion following cardiopulmonary compromise.

## Linked entities

- **Diseases:** cardiac arrest (MONDO:0000745), pulmonary embolism (MONDO:0005279)

## Full-text entities

- **Genes:** PLAT (plasminogen activator, tissue type) [NCBI Gene 5327] {aka T-PA, TPA}
- **Diseases:** cerebral dysfunction (MESH:D002547), hyperlipidemia (MESH:D006949), Thalamic Stroke (MESH:D013786), airspace disease (MESH:D004194), bilateral vertical gaze palsy (MESH:C565077), pupillary (MESH:D011681), pain (MESH:D010146), sleep disturbances (MESH:D012893), diabetes (MESH:D003920), Cardiac Arrest (MESH:D006323), anoxic brain injury (MESH:D002534), pleural effusion (MESH:D010996), cerebral edema (MESH:D001929), unresponsiveness (MESH:C567934), vascular complications (MESH:D003925), Pulmonary Embolism (MESH:D011655), Saddle emboli (MESH:D020766), seizures (MESH:D012640), ischemia (MESH:D007511), hypotensive (MESH:D007022), hypoxia (MESH:D000860), thrombotic (MESH:D013927), dysphagia (MESH:D003680), doll eye movement (MESH:D015835), hypersomnolence (MESH:D006970), occlusion of (MESH:D001157), hypertension (MESH:D006973), ischemic injury (MESH:D017202), neurovascular complications (MESH:D013901), sudden death (MESH:D003645), acidosis (MESH:D000138), Infarctions (MESH:D007238), embolic (MESH:D004617), diabetic ketoacidosis (MESH:D016883), hypoxic-ischemic injury (MESH:D020925), septic shock (MESH:D012772), motor defects (MESH:D000068079), comatose (MESH:D003128), cognitive impairments (MESH:D003072)
- **Chemicals:** beta-hydroxybutyrate (MESH:D020155), oxygen (MESH:D010100), lactic acid (MESH:D019344), epinephrine (MESH:D004837), metronidazole (MESH:D008795), norepinephrine (MESH:D009638), insulin (MESH:D007328), Blood glucose (MESH:D001786), Bicarb (MESH:D017693), PCO2 (-), cefazolin (MESH:D002437), antiXa (MESH:D006493), PO2 (MESH:C093415), glucose (MESH:D005947)
- **Species:** Staphylococcus lugdunensis (species) [taxon 28035], Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12921652/full.md

## References

14 references — full list in the complete paper: https://tomesphere.com/paper/PMC12921652/full.md

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Source: https://tomesphere.com/paper/PMC12921652