# Epidemiological Landscape of Breast Cancer in Northern India: A Narrative Review of Jammu and Kashmir

**Authors:** Gita Devi, Mittal Rathod, Mehul Kaliya, Aneri Rathod

PMC · DOI: 10.7759/cureus.101945 · Cureus · 2026-01-20

## TL;DR

This paper reviews breast cancer trends in Jammu and Kashmir, highlighting late diagnosis, low awareness, and high psychological stress among patients.

## Contribution

The study provides a synthesized overview of breast cancer epidemiology and psychosocial factors in Jammu and Kashmir, emphasizing regional-specific challenges.

## Key findings

- Breast cancer in J&K is diagnosed at a younger age and later stages, particularly in Kashmir.
- Low screening rates and awareness contribute to delayed detection and high psychological burden.
- Infiltrating ductal carcinoma and HR+/HER2- subtype are most common in the region.

## Abstract

Breast cancer is increasingly affecting younger women across India, with the Union Territory (UT) of Jammu and Kashmir (J&K) experiencing a similar shift. Limited regional data and poor screening access contribute to late diagnosis and high psychosocial burden, necessitating a synthesized evaluation of existing evidence. The objective of this review is to summarize and critically appraise the published literature on breast cancer in Jammu and Kashmir, with a specific focus on its epidemiology, clinical characteristics, molecular subtype distribution, awareness levels, and psychosocial determinants. A narrative review approach was adopted. Studies published in English and conducted within J&K were searched through PubMed, MEDLINE, and Google Scholar. Eligible studies included those reporting epidemiology, staging, molecular patterns, risk awareness, and mental-health outcomes. Data were extracted and synthesized according to the study characteristics. A total of 12 studies were included. Findings revealed a younger pattern of onset, with most cases detected between the late 30s and early 60s. Late-stage presentation (≥ stage III) was predominant, especially in Kashmir. Infiltrating ductal carcinoma and HR+/HER2- subtype were the most common. Awareness and screening rates were low, particularly among women >40 years. High levels of depression, anxiety, and post-traumatic stress disorder (PTSD) were reported among patients in Jammu. Mobile mammography initiatives showed high feasibility but poor follow-up linkage. Breast cancer in J&K is characterized by late diagnosis, distinct molecular patterns, limited awareness, and high psychological burden. Strengthening community-level screening, establishing population-based cancer registries, expanding mobile mammography programs, and integrating psycho-oncology into cancer care are crucial for improving early detection and outcomes in the UT.

## Linked entities

- **Diseases:** breast cancer (MONDO:0004989), depression (MONDO:0002050), anxiety (MONDO:0005618), post-traumatic stress disorder (MONDO:0005146)

## Full-text entities

- **Genes:** NR4A1 (nuclear receptor subfamily 4 group A member 1) [NCBI Gene 3164] {aka GFRP1, HMR, N10, NAK-1, NGFIB, NP10}, ERBB2 (erb-b2 receptor tyrosine kinase 2) [NCBI Gene 2064] {aka CD340, HER-2, HER-2/neu, HER2, MLN 19, MLN-19}
- **Diseases:** Cardiovascular Diseases (MESH:D002318), TNBC (MESH:D064726), Depression (MESH:D003866), Breast Cancer (MESH:D001943), IDC (MESH:D044584), Anxiety (MESH:D001007), Diabetes (MESH:D003920), Cancer (MESH:D009369), Psychiatric comorbidities (MESH:D001523), Stroke (MESH:D020521), obesity (MESH:D009765), anxiety disorders (MESH:D001008), emotional distress (MESH:D012128), PTSD (MESH:D013313)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12921269/full.md

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12921269/full.md

## References

22 references — full list in the complete paper: https://tomesphere.com/paper/PMC12921269/full.md

---
Source: https://tomesphere.com/paper/PMC12921269