# Ubiquitination at pericentromeric regions: directing heterochromatin reassembly during cell division

**Authors:** Zhenxuan Chen, Tiebang Kang, Liwen Zhou

PMC · DOI: 10.1038/s41392-026-02590-y · Signal Transduction and Targeted Therapy · 2026-02-20

## Full-text entities

- **Genes:** CBX5 (chromobox 5) [NCBI Gene 23468] {aka HEL25, HP1, HP1A, HP1alpha}, CDK1 (cyclin dependent kinase 1) [NCBI Gene 983] {aka CDC2, CDC28A, P34CDC2}, CUL5 (cullin 5) [NCBI Gene 8065] {aka CUL-5, VACM-1, VACM1}, SUV39H1 (SUV39H1 histone lysine methyltransferase) [NCBI Gene 6839] {aka H3-K9-HMTase 1, KMT1A, MG44, SUV39H}, CCNB1 (cyclin B1) [NCBI Gene 891] {aka CCNB}, ASB7 (ankyrin repeat and SOCS box containing 7) [NCBI Gene 140460], SUV39H2 (SUV39H2 histone lysine methyltransferase) [NCBI Gene 79723] {aka KMT1B}, SETDB1 (SET domain bifurcated histone lysine methyltransferase 1) [NCBI Gene 9869] {aka ESET, H3-K9-HMTase4, KG1T, KMT1E, TDRD21}, G2E3 (G2/M-phase specific E3 ubiquitin protein ligase) [NCBI Gene 55632] {aka KIAA1333, PHF7B}
- **Diseases:** tumor (MESH:D009369)
- **Chemicals:** DAPI (MESH:C007293), H3K14ub (-)
- **Species:** Saccharomyces cerevisiae (baker's yeast, species) [taxon 4932], Homo sapiens (human, species) [taxon 9606]

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Source: https://tomesphere.com/paper/PMC12920882