# Contact with dogs is associated with improved survival in cancer patients

**Authors:** Robert Preissner, Zhengjie Yang, Saskia Preissner, Christa Thöne-Reineke

PMC · DOI: 10.1038/s41598-026-39952-z · Scientific Reports · 2026-02-17

## TL;DR

Owning a dog is linked to better survival rates in cancer patients, possibly due to increased activity and emotional support.

## Contribution

First large-scale study showing dog ownership is associated with reduced cancer mortality.

## Key findings

- Dog ownership was associated with a 64% relative risk reduction in cancer mortality.
- Survival analysis showed a 5-year cumulative survival rate with a hazard ratio of 0.36 for dog owners.
- Potential mechanisms include physical activity, psychosocial support, and microbiome changes.

## Abstract

For cardiovascular diseases, diabetes, and asthma, the positive effects of dog ownership are shown. Cancer is a leading cause of death, but the influence of dogs on cancer incidence and survival is not well examined. As modifiable lifestyle factors gain importance in cancer survivorship research, the potential protective role of dog ownership warrants systematic investigation. We retrospectively analyzed clinical data from a federated global health research network, focusing on patients diagnosed with cancer (International Classification of Diseases (ICD-10): C00-D49). From these, we generated two cohorts with contact with dogs (cohort 1) and one without (cohort 2). After propensity score matching for age and sex, a total of about 55,000 patients were included. Analysis of the matched cohort demonstrated that dog ownership was significantly associated with reduced 5-year all-cause mortality in cancer patients compared to non-owners (RR = 0.44). Survival analysis revealed a significantly higher 5-year cumulative survival rate among dog-owning patients versus non-owners, with a hazard ratio (HR) of 0.36. Contact with dogs is associated with a 64% relative risk reduction in cancer mortality, potentially mediated by increased physical activity, psychosocial support, and microbiome modulation. While retrospective design precludes causal inference, this first large-scale matched cohort study provides compelling epidemiological evidence warranting prospective validation.

## Linked entities

- **Diseases:** cancer (MONDO:0004992)

## Full-text entities

- **Diseases:** International (MESH:D000082122), depression (MESH:D003866), breast and prostate cancer (MESH:D001943), type 2 diabetes (MESH:D003924), ischemic stroke (MESH:D002544), Cancer (MESH:D009369), allergic rhinitis (MESH:D065631), diabetes (MESH:D003920), cardiovascular diseases (MESH:D002318), lung cancer (MESH:D008175), myocardial infarction (MESH:D009203), anxiety (MESH:D001007), asthma (MESH:D001249), muscle atrophy (MESH:D009133), chronic inflammation (MESH:D007249), death (MESH:D003643), hypertension (MESH:D006973)
- **Chemicals:** alcohol (MESH:D000438), short-chain fatty acid (MESH:D005232)
- **Species:** Homo sapiens (human, species) [taxon 9606], Canis lupus familiaris (dog, subspecies) [taxon 9615]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12920787/full.md

## References

2 references — full list in the complete paper: https://tomesphere.com/paper/PMC12920787/full.md

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Source: https://tomesphere.com/paper/PMC12920787