# Lung Adenocarcinoma With Intratumoral Necrosis Induced by Bronchial Artery Embolization

**Authors:** Ikumi Kashiwagi, Akihiko Sokai, Mamoru Takahashi, Akihiro Takahagi, Harutaro Okada, Toshiyuki Iwata, Yasuyuki Hayashi, Yuki Sakai, Naoaki Yasuda, Miki Tasato, Saki Kusunoki, Toshihide Yamaoka, Takashi Nishimura

PMC · DOI: 10.1002/rcr2.70520 · Respirology Case Reports · 2026-02-19

## TL;DR

A 70-year-old woman with lung cancer had her tumor shrink after a procedure to stop bleeding, leading to long-term remission.

## Contribution

This case report highlights bronchial artery embolization's potential to induce tumor necrosis and enable curative resection in lung adenocarcinoma.

## Key findings

- Bronchial artery embolization led to tumor necrosis and cavitation in a lung adenocarcinoma case.
- The patient remained recurrence-free for over 5 years after surgery and chemotherapy.

## Abstract

A 70‐year‐old woman presented with hemoptysis due to a right upper lobe mass. Bronchial artery embolization (BAE) using gelatin sponge was successful in controlling bleeding. Two weeks later, chest computed tomography (CT) revealed that the solid tumour had been replaced by a 5.6 cm thin‐walled cavity without fluorodeoxyglucose uptake on positron emission tomography–computed tomography, although fluorodeoxyglucose accumulation was observed in the right hilar lymph node. Right upper lobectomy confirmed adenocarcinoma. The patient, confirmed with a pathological stage of IIIA, received adjuvant chemotherapy and has remained recurrence‐free for more than 5 years. This case suggests that BAE induced tumour necrosis and cavitation; however, viable tumour tissue remained. Further accumulation of similar cases is needed to clarify the therapeutic significance of BAE in lung cancer.

We report a case of lung adenocarcinoma in which bronchial artery embolization induced tumour necrosis and cavitation, facilitating curative resection and leading to long‐term disease‐free survival.

## Linked entities

- **Diseases:** lung adenocarcinoma (MONDO:0005061)

## Full-text entities

- **Genes:** CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}
- **Diseases:** smoker (MESH:C000719328), ischemic necrosis (MESH:D005271), lung cancer (MESH:D008175), adenocarcinoma (MESH:D000230), tumour (MESH:D009369), Achilles tendon rupture (MESH:D012421), Hemoptysis (MESH:D006469), cavitary (MESH:C566924), Lung Adenocarcinoma (MESH:D000077192), bleeding (MESH:D006470), hepatocellular carcinoma (MESH:D006528), Necrosis (MESH:D009336), BAE (MESH:D001982)
- **Chemicals:** oxygen (MESH:D010100), BAE (-), cisplatin (MESH:D002945), fluorodeoxyglucose (MESH:D019788), eosin (MESH:D004801)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

5 references — full list in the complete paper: https://tomesphere.com/paper/PMC12920670/full.md

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Source: https://tomesphere.com/paper/PMC12920670