# Editorial: Impact of oral and gut microbiome on health and diseases

**Authors:** Subhadeep Das, Jonathan B. Clayton, Soumyadev Sarkar

PMC · DOI: 10.3389/fcimb.2026.1792511 · Frontiers in Cellular and Infection Microbiology · 2026-02-06

## Full-text entities

- **Genes:** TNF (tumor necrosis factor) [NCBI Gene 7124] {aka DIF, IMD127, TNF-alpha, TNFA, TNFSF2, TNLG1F}, OCLN (occludin) [NCBI Gene 100506658] {aka BLCPMG, PPP1R115, PTORCH1}, IL6 (interleukin 6) [NCBI Gene 3569] {aka BSF-2, BSF2, CDF, HGF, HSF, IFN-beta-2}, IL1B (interleukin 1 beta) [NCBI Gene 3553] {aka IL-1, IL1-BETA, IL1F2, IL1beta}, GFAP (glial fibrillary acidic protein) [NCBI Gene 2670] {aka ALXDRD}, MIR21 (microRNA 21) [NCBI Gene 406991] {aka MIRN21, hsa-mir-21, miR-21, miRNA21}, MIR155 (microRNA 155) [NCBI Gene 406947] {aka MIRN155, miRNA155, mir-155}, NFKB1 (nuclear factor kappa B subunit 1) [NCBI Gene 4790] {aka CVID12, EBP-1, KBF1, NF-kB, NF-kB1, NF-kappa-B1}, TJP1 (tight junction protein 1) [NCBI Gene 7082] {aka ZO-1}
- **Diseases:** sleep disturbances (MESH:D012893), AUD (MESH:D000437), PC (MESH:D010190), Yin-deficiency (MESH:D016710), dental caries (MESH:D003731), periodontitis (MESH:D010518), abscesses (MESH:D000038), inflammation (MESH:D007249), prostate cancer (MESH:D011471), renal fibrosis (MESH:D005355), ocular infections (MESH:D015817), cardiometabolic and (MESH:D024821), prediabetes mellitus (MESH:D011236), BTC (MESH:D001661), PMO (MESH:D010024), meningitis (MESH:D008580), benign prostatic hyperplasia (MESH:D011470), CKD (MESH:D051436), neuroinflammatory (MESH:D000090862), CVDs (MESH:D002318), DM (MESH:D003920), gastrointestinal disorders (MESH:D005767), Microbial dysbiosis (MESH:D064806), colitis (MESH:D003092), cancer (MESH:D009369), fatigue (MESH:D005221), MSA (MESH:D019578), systemic (MESH:D015619), heart (MESH:D006331), MAFLD (MESH:D005234), OSA (MESH:D020181), T2DM (MESH:D003924), cardiac failure (MESH:D006333), breast cancer (MESH:D001943), obesity (MESH:D009765), infective endocarditis (MESH:D004696), GIB (MESH:D006471), UC (MESH:D003093), bloodstream infections (MESH:D018805), chronic diseases (MESH:D002908), chronic prostatitis (MESH:D011472), infectious diseases (MESH:D003141), frailty (MESH:D000073496), HIV (MESH:D015658), MDD (MESH:D003865), AIS (MESH:D000083242), intestinal disease (MESH:D007410), PD (MESH:D010510)
- **Chemicals:** nitrate (MESH:D009566), fat (MESH:D005223), pentose phosphate (MESH:D010428), nitrite (MESH:D009573), Ile (MESH:D007532), steroid (MESH:D013256), MP (MESH:D000080545), alcohol (MESH:D000438)
- **Species:** Trichomonas tenax (species) [taxon 43075], Porphyromonas gingivalis (species) [taxon 837], Aggregatibacter actinomycetemcomitans (species) [taxon 714], Streptococcus oralis (species) [taxon 1303], Homo sapiens (human, species) [taxon 9606], Staphylococcus (genus) [taxon 1279], Mus musculus (house mouse, species) [taxon 10090], Mediterraneibacter gnavus (species) [taxon 33038], Fusobacterium nucleatum (species) [taxon 851], Pseudomonas (RNA similarity group I, genus) [taxon 286], Bacillota (clostridial firmicutes, phylum) [taxon 1239], gut metagenome (species) [taxon 749906], Entamoeba gingivalis (species) [taxon 38877], Erysipelatoclostridium [taxon 1505663], Enterococcus (genus) [taxon 1350]

## Full text

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Source: https://tomesphere.com/paper/PMC12920484